in this article the general non-symmetric parametric form of the incremental secant stiffness matrix for nonlinear analysis of solids have been investigated to present a semi analytical sensitivity analysis approach for geometric nonlinear shape optimization. to approach this aim the analytical formulas of secant stiffness matrix are presented. the models were validated and used to perform inve...

In this article the general non-symmetric parametric form of the incremental secant stiffness matrix for nonlinear analysis of solids have been investigated to present a semi analytical sensitivity analysis approach for geometric nonlinear shape optimization. To approach this aim the analytical formulas of secant stiffness matrix are presented. The models were validated and used to perform inve...

We use Hodge-type orthogonal decompositions for studying the compatibility equations of the displacement gradient and the linear strain with prescribed boundary displacements. We show that the displacement gradient is compatible if and only if for any equilibrated virtual first-Piola Kirchhoff stress tensor field, the virtual work done by the displacement gradient is equal to the virtual work d...

Gaps in communication between medical officers and poor planning are associated with prescribing errors and may result in patient harm. This study describes medication communication on post-take ward rounds (PTWR). Over 6 weeks on 24 PTWR, 130 patients, prescribed 1244 medications, were observed. Of these, 811 (65%) medications were discussed, with 249 discussions (relating to 126 medications) ...

Prescribing is a characteristic role of a medical practitioner. On graduating from medical school, students are presumed to have acquired the necessary pharmacology knowledge underpinning the therapeutics and developed their personal skills and behaviors in order to write a safe and effective prescription (The Four Ps). However, there are reports of errors in medical prescribing and dissatisfie...

This paper reports on a multiple-case study of prescribing by nurse specialists in Dutch hospital settings. Most analyses of interprofessional negotiations over professional boundaries take a macro sociological approach and ignore workplace jurisdictions. Yet boundary blurring takes place and healthcare professionals renegotiate formal policies in the workplace. This paper studies the division ...

The innovation of penicillin by Dr Alexander Fleming in 1928 and its use in clinical practice saved many lives, especially during the Second World War. Tuberculosis still carries a significant public health threat and has re-emerged over the past two decades, even in modern countries where tuberculosis was thought to be eliminated. The World Health Organization defines antimicrobial resistance ...