introduction: gestational stress can lead to cerebral functional disorders, such as epilepsy, probably due to the disturbance in the cerebral maturation and causing abnormal neuronal correlations. in the present study, effect of gestational predator stress on the neonatal epileptic behaviors was investigated in rats. methods: female rats (200 ± 20 g) were divided into two groups intact pregnant...

objective(s):the hippocampus has been implicated in pathophysiology of schizophrenia. prenatal stress is a contributing risk factor for a wide variety of neuropsychiatric diseases including schizophrenia. this study examined long-term effects of prenatal restraint stress on the stereological parameters in the cornu ammonis (ca) of adult male rats as an animal model of schizophrenia. materials a...

background & aim: although pregnancy seems to be a pleasant experience in a women’s life, the accompanied physical and psychological changes lead to high levels of stress in mothers. prenatal stress widely affects the physical and mental health of mothers and infants; therefore, adopting appropriate coping strategies are highly required. considering the importance of coping strategies in psycho...

Prenatal stress is reported to increase the risk of nervous, endocrine and metabolism diseases, immune dysfunction. The influence of prenatal stress on immune system is complicated, which include the changes of immune cells, cytokines, immune organs, hematopoietic stem cells. The mechanism accepted is that prenatal stress cause secretion changes of stress hormones like adrenaline and glucocorti...

objective(s) it is well known that prenatal stresses (ps) induce a variety of neurobiological and behavioral alterations, some of them involving the hippocampal formation. this study aimed to determine whether restraint stress influences the neuronal volume and number of granule cells in the hippocampus of adult rat offspring. materials and methods ten wistar pregnant rats were randomly divided...

introduction: prenatal stress has deleterious effects on the development of the brain and is associated with behavioral and psychosocial problems in childhood and adulthood. this study aimed to determine the protective effect of l-arginine on fetal brain under maternal stress. methods: twenty pregnant wistar rats (weighting 200-230 g) were randomly divided into 4 groups (n=5 for each group). th...

Chronic psychological stress is a risk factor for osteoporosis. Maternal active mastication during prenatal stress attenuates stress response. The aim of this study is to test the hypothesis that maternal active mastication influences the effect of prenatal stress on bone mass and bone microstructure in adult offspring. Pregnant ddY mice were randomly divided into control, stress, and stress/ch...

Exposure to prenatal and early-life stress results in alterations in neural connectivity and an increased risk for neuropsychiatric disorders. In particular, alterations in amygdala connectivity have emerged as a common effect across several recent studies. However, the impact of prenatal stress exposure on the functional organization of the amygdala has yet to be explored in the prematurely-bo...

Prenatal stress can cause long-term effects on cognitive functions in offspring. Hippocampal synaptic plasticity, believed to be the mechanism underlying certain types of learning and memory, and known to be sensitive to behavioral stress, can be changed by prenatal stress. Whether enriched environment treatment (EE) in early postnatal periods can cause a recovery from these deficits is unknown...