Nicotine caused significant increase in the serum Cholesterol, Triglyceride, VLDL, LDL & significant reduction in HDL level. Premna integrifolia & Atorvastatin treatment showed significant prevention in increased serum Cholesterol, Triglyceride, LDL as compared to Nicotine control (NC) group. While HDL level was significantly increased in treated & standard group as compared to Nicotine control...

Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. Materials and methods: Neuropharmacology study was done by open field and hole cro...

Leaves of Premna integrifolia belong to Verbanacea is an important rasayana drug in ayurvedic medicine and are considered to be useful in the treatment of variety of ailments. The present study was aimed to assess the for its antioxidant activities. The flavonoid rich fraction, showed antioxidant activity was evaluated using the superoxide scavenging, anti lipid peroxidation, hydroxyl radical s...

OBJECTIVE Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. MATERIALS AND METHODS Neuropharmacology study was done by open field and hole cro...

Premna integrifolia Linn (Family: Verbenaceae) synonyms of Premna serratifolia has tremendous medicinal value. The methanolic extract of Premna integrifolia (MEPI) bark was subjected to investigate its antidiabetic activity along with its in vitro antioxidant activity. Oral glucose tolerance test (OGTT), normoglycemic test and alloxan induced diabetic test was consider for antidiabetic activity...

objective: premna integrifolia linn (family: verbenaceae) synonym of premna serratifolia has tremendous medicinal value. preliminary pharmacological studies were performed on the methanolic extract of premna integrifolia (mepi) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. materials and methods: neuropharmacology study was done by open field and hole cro...

Premna integrifolia Linn. roots are used in the Indian system of medicine for the treatment of diabetes, inflammation, liver disorders etc. The present study was aimed to investigate the antioxidant activity of Premna integrifolia L. (Family: Verbenaceae) in CCl4 (carbon tetrachloride) induced oxidative stress in SpragueDawley rats. CCl4 injection induced oxidative stress by a significant rise ...

Premna integrifolia Linn. is a medicinal plant used in "Dhasamula" drug preparation of Ayurvedic systems of medicine in the treatment of various ailments like bronchitis, dyspepsia, liver disorders, piles, constipation, hyperlipidemia and fever. The anti-atherosclerotic activity of hydroalcoholic extract (HAE) of root bark of P. integrifolia was evaluated in high fat diet induced atherosclerosi...

Premna serratifolia Linn. (syn: Premna integrifolia) is one the most widely used plant in the Ayurvedic system of medicine. Several pharmacological activities including antioxidant effects and phytochemical investigations have been previously reported for the various parts of plant, except the root woody tissues. In the present study, the antioxidant activity and active principle of the root wo...