Overseas investigations have shown that many healthcare institutions are understocked of antidotes to treat these patients. 1–4 Despite a recent study to the contrary, 5 the paper by Fountain and colleagues, published in this issue of the New Zealand Medical Journal, suggests similar problems in New Zealand hospitals with shortcomings in hospital pharmacy stocks and resupply. 6 The paper raises...

stability studies play a critical role in assuring product quality at all points in the vaccine life cycle. these studies used to determine vaccine expiry date and vaccine efficacy. accelerated stability and long term stability study performed for three batches of trivalent oral poliomyelitis vaccine (opv) and three batches of monovalent opv (type1) manufactured by razi institute. after samplin...

introduction: response to morphine and role of nitric oxide (no) on expression of morphine response has been studied in vertebrates. but, little evidence is provided in the matter in earlier invertebrates. this investigation for the first time evaluated the effect of no on expression of morphine potency in paramecium caudatum. methods: animal after isolation from natural media and specific iden...

vaccination against mumps is included in world health organization (who) program of global immunization. safety and efficacy of vaccines must be confirmed by control units in charge of public health. in iran, the secondary control on potency of vaccine has not been set up yet. we decided to overcome this problem by developing who and nibsc methods in food and drug control lab. ‎nine dilutions o...

Nineteen linkage groups containing a total of 52 markers have been identified in the sheep genome after typing large paternal half-sib families. The linkage groups range in size from 2 markers showing no recombination to a group containing 6 markers covering approximately 30 cM of the sheep genome. Thirteen of the groups have been assigned to a sheep chromosome. Three groups contain markers fro...

The high-resolution spectrum of water vapor between 13 200 and 16 500 cm-1 recorded by J.-Y. Mandin, J-P. Chevillard, C. Camy-Peyret, J.-M. Flaud, and J. W. Brault (1986. J. Molec. Spectrosc., 116, 167) is analyzed using high-accuracy linelists obtained using ab initio calculations and spectroscopically determined potential. Assignments to H216O transitions are presented for 663 of the 795 unas...

We consider the problem of assigning flights to airport gates. We examine the general case in which an aircraft serving a flight may be assigned to different gates for arrival and departure processing and for optional intermediate parking. Restrictions to this assignment include gate closures and shadow restrictions, i. e. the situation where certain gate assignments may cause blocking of neigh...

background: potency test for control of rubella vaccine is a significant factor to qualify production line and vaccination pro­gram. for this reason, who recommends to use the microtitration method by both vaccine companies and control laborato­ries. then the study was done to improve this test. methods: three rubella virus samples, including an in-house standard, a lot of vaccine and an in- pr...

for evaluation the stability and potency of anthrax vaccine prepared in razi vaccine and serum research institute in iran, samples of different batches of vaccine were kept at 4-8 °c (refrigerator), 20-25 °c (room temperature) and 37 °c (incubator).the viable spores/ml of vaccines were determined using plate–counting method before and after holding at different temperatures monthly. vaccine pot...

mass vaccination against viral infections such as mumps is a very noticeable and appropriate attempt in common health. mumps infection has severe complications like deafness, infertility and meningitis. attenuated live vaccine of mumps is produced and used to prevent the problems. viral content in the monovalent vaccine is assayed with different methods. nowadays international standards introdu...