Prevention of oxidative DNA damage due to hydroxyl radical is important for the prevention and treatment of disease. Because of their widely recognized antioxidant ability, 12 polyphenolic compounds were assayed by gel electrophoresis to directly quantify the inhibition of DNA damage by polyphenols with Fe(2+) and H2O2. All of the polyphenol compounds have IC50 values ranging from 1-59 microM a...

in this study, the effect of salicylic acid (sa) on root knot nematode (meloidogyne javanica) pathogenicity and induction of some defense mechanisms such as polyphenol oxidase enzyme activity and total phenol accumulation were investigated in greenhouse conditions. we demonstrated that application of 5mm salicylic acid through foliar spray could induce resistance against m. javanica in tomato. ...

Polyphenol prevention of iron-mediated DNA damage occurs primarily through iron binding. Once bound, iron in the Fe(2+)-polyphenol complex autooxidizes to Fe(3+) in the presence of O(2). To determine the correlation between the rate of Fe(2+)-polyphenol autooxidation and polyphenol antioxidant ability, kinetic studies at pH = 6.0 in the presence of oxygen were performed using UV-vis spectrophot...

The study shows the changes of total polyphenol compounds and antioxidant activities of Polygonum multiflorum Thunb root extract during the preservation time by freezing method. In addition, the treatment of initially raw materials by drying process also affects strongly total polyphenol compounds and antioxidant activity. Total phenolic compounds were determined by the Folin Ciocalteu method a...

Background Polyphenols are naturally derived bioactive compounds that have been attributed numerous health benefits. We have previously characterized the beneficial effect of a polyphenol enriched apple extract in a murine model of food allergy. The objective of the current study was to elucidate the class of bioactive polyphenols that are implicated in the beneficial anti-allergic effect of po...

Inhibition of copper-mediated DNA damage has been determined for several polyphenol compounds. The 50% inhibition concentration values (IC(50)) for most of the tested polyphenols are between 8 and 480 μM for copper-mediated DNA damage prevention. Although most tested polyphenols were antioxidants under these conditions, they generally inhibited Cu(I)-mediated DNA damage less effectively than Fe...

Polyphenol compounds were extracted from Myrtus communis L. berries (Myrtaceae) by maceration in 70% ethanol and analysed by HPLC-DAD and electrospray mass spectrometry. The Myrtus berries were collected at maturity from seven localities on the island of Corsica (France) and the sampling was carried out during three years. The polyphenol composition of Corsican Myrtus berries was characterized ...

The effect of nonthermal pulsed electric field (PEF) and thermal treatment (900C for 60s) was studied on quality parameters of Emblica officinalis juice for the period of 6 weeks at 40C using monopolar rectangular pulse of 1μs width. The PEF treatment was given using static chamber at 24kV/cm for 500μs. The quality of Emblica officinalis juice was investigated in terms of non enzymatic browning...