using of colloids and polymeric microparticles are gradually increasing. it is observed that thepositive effects of particles stems in both traditional applications such as column pickings,coatings and paints to more recent technologies in diagnostics, drug delivery and optical devicesare well documented. this review focuses on importance of colloids and covers theirapplications on three level:...

BACKGROUND/PURPOSE The purpose of this research was to develop an alternative adjuvant for hepatitis B vaccine (HBsAg) that elicits a long-lasting immune response after a single administration. In this study, the suitability of Poly (D, L)-lactide-co-glycolic acid (PLGA), Poly lactic acid (PLA) and Chitosan polymers as adjuvants for HBsAg were investigated. METHODS We used solvent evaporation...

Using of colloids and polymeric microparticles are gradually increasing. It is observed that the positive effects of particles stems in both traditional applications such as column pickings, coatings and paints to more recent technologies in diagnostics, drug delivery and optical devices are well documented. This review focuses on importance of colloids and covers their applications on three le...

Microspheres have been prepared from the resorbable linear polyester of beta-hydroxybutyric acid (polyhydroxybutyrate, PHB) by the solvent evaporation technique and investigated in vitro and in vivo. Biocompatibility of the microspheres has been proved in tests in the culture of mouse fibroblast cell line NIH 3T3 and in experiments on intramuscular implantation of the microspheres to Wistar rat...

A new and simple method for testing and classifying the bioadhesive behavior of polymeric microparticles,with or without drugs is presented. The method is used to determine the adhesive forces between solid polymeric microparticles of diameter up to 200 pm in contact with natural rn~os~ or with a mucin gel. A t~oret~ul analysis is presented in order to calcu~te the ~~sive c~r~ter~tics of spheri...

Using of colloids and polymeric microparticles are gradually increasing. It is observed that the positive effects of particles stems in both traditional applications such as column pickings, coatings and paints to more recent technologies in diagnostics, drug delivery and optical devices are well documented. This review focuses on importance of colloids and covers their applications on three le...

A simple stability-indicating HPLC-DAD method was validated for the determination of ferulic acid (FA) in polymeric microparticles. Chromatographic conditions consisted of a RP C18 column (250 mm × 4.60 mm, 5 μm, 110 Å) using a mixture of methanol and water pH 3.0 (48 : 52 v/v) as mobile phase at a flow rate of 1.0 mL/min with UV detection at 320 nm. The developed method was validated as per IC...

Polymeric microparticles can serve as carriers or sensors to instruct or characterize tissue biology. However, incorporating microparticles into tissues for in vitro assays remains a challenge. We exploit three-dimensional cell-patterning technologies and directed epithelial self-organization to deliver microparticles to the lumen of reconstituted human intestinal microtissues. We also develop ...

Herein we demonstrate how the volatility of a liquid can be manipulated by enclosing microdroplets of the liquid into thin polymeric shells. In this way, composite core-shell microparticles consisting of 80 wt% of a liquid core material and 20 wt% of a polymer can be made 150 °C more stable than the individual core component. The thermal stability of the composite microparticles is found to be ...

Polymeric particulate delivery systems are vastly explored for the delivery of chemotherapeutic agents. However, the preparation of polymeric particulate systems with the capability of providing sustained release of two or more drugs is still a challenge. Herein, poly (D, L-lactic-co-glycolic acid, 50:50) hollow microparticles co-loaded with doxorubicin and paclitaxel were developed through dou...