The aim of the present research was to study the effects of weak cation exchange resins, polacrilex with exchangeable H+ and polacrillin potassium and strong cation exchange resin sodium polystyrene sulfonate on water uptake behavior of ranitidine hydrochloride. Drug resin complexes (DRC) were prepared and evaluated for the percentage of moisture gain when placed in a humidity c...

the aim of the present research was to study the effects of weak cation exchange resins, polacrilex with exchangeable h+ and polacrillin potassium and strong cation exchange resin sodium polystyrene sulfonate on water uptake behavior of ranitidine hydrochloride. drug resin complexes (drc) were prepared and evaluated for the percentage of moisture gain when placed in a humidity chamber at 40e2 °...

BACKGROUND The use of nicotine replacement therapy (NRT) can almost double the chances of success for smokers to quit. Nevertheless, there is still a considerable number of cessation attempts that are made without any treatment. This novel oral formulation, (lozenge containing nicotine bitartrate dihydrate) has been developed to enlarge the offer for efficient smoking cessation drug therapies, ...

BACKGROUND Standard, generic self-help materials have been largely ineffective as behavioral treatments for smoking cessation. In contrast, self-help programs tailored to the needs of specific smokers have shown promise in facilitating quitting. OBJECTIVE To evaluate the incremental efficacy of the Committed Quitters Program (CQP), a set of computer-tailored materials offered to purchasers of...

We present a patient with central serous chorioretinopathy (CSCR) associated choroidal neovascularization (CNV), who received multiple ranibizumab injections. The patient showed initial improvement with the therapy after which there was an increase in macular thickness. On reviewing his systemic history it was noted that he had been recently put on nicotine replacement therapy (NRT). On stoppin...

T he availability of nicotine polacrilex as an adjunct to smoking cessation offers another way for primary care and chest physicians to become involved in one of the most important aspects of preventive medicine in our time. While accompanying package information and literature are helpful, there are many unanswered questions regarding actual practical applications. The following relates my rec...

BACKGROUND New ways of improving the efficacy of nicotine therapy need to be explored. We tested whether starting nicotine polacrilex gum treatment 4 weeks before the quit date improved smoking abstinence rates compared with starting treatment on the quit date. METHODS An open randomized trial of 314 daily smokers (mean, 23.7 cigarettes/d) enrolled through the Internet and by physicians in Sw...

Self-Help Manuals 100 Efficacy 100 Relevant Process Measures 101 Summary 102 Minimal Clinical Interventions 102 Efficacy 104 Relevant Process Measures 105 Summary 105 Intensive Clinical Interventions 105 Problem Solving/Skills Training 106 Rapid Smoking 107 Other Aversive-Smoking Strategies 108 Cue Exposure 108 Nicotine Fading 109 Motivational Rewards 110 Social Support 110 Weight Control 111 H...