نتایج جستجو برای: Platelet Aggregation Inhibitors/Adverse Effects

تعداد نتایج: 1687119  

ایمنی, بهزاد , صفی‌آریان, رضا , قاضی خانلو ثانی, کریم , منافی, بابک , کرمپوریان, آرزو ,

Background: Platelet activation and aggregation plays an essential role in the for-mation of coronary artery thrombosis. Nowadays, the Clopidogrel is administered oral-ly as an inhibitor of platelet aggregation. Due to the high price of the original brand of Clopidogrel (Plavix), an Iranian brand of Clopidogrel (Osvix) has been produced. This study was conducted to evaluate the effectiveness, s...

MA Fahim S Singh

When tobacco is smoked, chewed or snuffed, nicotine is absorbed by the lungs or mucous membrane and quickly moved into the bloodstream, where it is circulated throughout the brain. In fact nicotine is highly dangerous to be consumed in any form. The present study was conducted to know the adverse effects of nicotine on the platelet aggregation in cerebral microvessels of mice. Male mice of aver...

MA Fahim S Singh

When tobacco is smoked, chewed or snuffed, nicotine is absorbed by the lungs or mucous membrane and quickly moved into the bloodstream, where it is circulated throughout the brain. In fact nicotine is highly dangerous to be consumed in any form. The present study was conducted to know the adverse effects of nicotine on the platelet aggregation in cerebral microvessels of mice. Male mice of aver...

A Hashemi Tayer, H Fakhar,

Abstract Introduction Platelet aggregation plays a significant role in the etiology of cardiovascular diseases. Therefore, treatments to inhibit platelet aggregation can reduce the risk of coronary thrombosis. Several studies indicated that garlic can inhibit platelet aggregation. This study aimed to determine the effect of garlic in comparison with Plavix on platelet aggregation. Materials ...

Journal: :iranian journal of pharmaceutical research 0
zahra lorigooini department of pharmacognosy, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran seyed abdolmajid ayatollahi department of pharmacognosy, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran phytochemistry research center, shahid beheshti university of medical sciences, tehran, iran salimeh amidi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran farzad kobarfard -

epidemiologic studies show that the cardiovascular diseases are associated with multiple factors such as raised serum total cholesterol, increased ldl, increased platelet aggregation, hypertension and smoking. in-vitro studies have confirmed the ability of some plants of allium species to reduce these parameters. therefore, we evaluated anti-platelet aggregation effect of some allium species (a...

Background: Patients undergoing cardiac surgery are at increased risk of bleeding due to multifactorial coagulopathies. In the present study, we aimed at investigating the changes in platelet count and function during and after surgery as well as determining the association of the platelet dysfunction with bleeding and transfusion requirements in these patients.    Methods: A total o...

Epidemiologic studies show that the cardiovascular diseases are associated with multiple factors such as raised serum total cholesterol, increased LDL, increased platelet aggregation, hypertension and smoking. In-vitro studies have confirmed the ability of some plants of Allium species to reduce these parameters. Therefore, we evaluated anti-platelet aggregation effect of some Allium species (A...

MA Fahim S Singh

Aloe vera plant (A. vulgari and A. barbadensis) has being used traditionally as a medicinal plant for centuries. Gel from the inner central zone of the leaves and latex from pericyclic cells are used for medicinal purposes. The present study was conducted to elucidate the beneficial effects of Aloe vera juice on the platelet aggregation in cerebral microvessels of mice. Male mice were injected ...

MA Fahim S Singh

Aloe vera plant (A. vulgari and A. barbadensis) has being used traditionally as a medicinal plant for centuries. Gel from the inner central zone of the leaves and latex from pericyclic cells are used for medicinal purposes. The present study was conducted to elucidate the beneficial effects of Aloe vera juice on the platelet aggregation in cerebral microvessels of mice. Male mice were injected ...

Journal: :iranian journal of pharmaceutical research 0
marjan esfahanizade department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. central research laboratories, shahid beheshti university of medical sciences, tehran, iran shohreh mohebbi department of medicinal chemistry, school of pharmacy, zanjan university of medical sciences, zanjan, iran. behnam dashtbozorg department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran salimeh amidi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran ali gudarzi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran seyed abdolmajid ayatollahi department of medicinal chemistry, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran phytochemistry research center, shahid beheshti university of medical sciences, tehran, iran

a series of novel 2-aminopyrimidine and 2-substituted-4,6-diaminopyrimidine derivatives have been synthesized and their anti platelet aggregation activities were assessed against adp and arachidonic acid- induced platelet aggregation in human plasma using light transmission aggregometry. none of the compounds showed satisfactory activity against the aggregation induced by adp. however, satisfac...

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