a-10-year-old girl was referred to our department for multiple hyperpigmented plaques. one  week  previously,  she  had  been  given  one  suppository  of  acetylsalicylic acid  – phenobarbital for fever. twelve hours after the drug intake the child developed pruritic red plaques on the left thigh. six weeks after resolution of the acute reaction, patch tests were performed separately, with phe...

Basal cell carcinoma (BCC) is the most common human malignancy. It occurs most often in elderly patients on the sun-exposed skin of the head and neck (1). ma skin cancer and is uncommon on unexposed skin such as the genital and perianal region (2). We report a 78-year-old otherwise healthy woman that was seen with a pigmented lesion originating on the right vulva. The lesion had started as a sm...

case: A 3.5-year-old girl presented with a 1-year history of a slow growing pigmented lesion on the dorsal aspect of her right foot. Physical examination revealed the presence of a pigmented patch with color distribution from pink to tan to dark brown, relatively well circumscribed and approximately 1.5 × 2cm with irregular borders, and especially a single dark central papule superimposed...

A-10-year-old girl was referred to our department for multiple hyperpigmented plaques. One week previously, she had been given one suppository of acetylsalicylic acid - phenobarbital for fever. Twelve hours after the drug intake the child developed pruritic red plaques on the left thigh. Six weeks after resolution of the acute reaction, patch tests were performed separately, with phenobarbital ...

Actinic lichen planus is a clinical variant of lichen planus, involving mainly sun-exposed areas and manifested as annular lesions with a pigmented center surrounded by a hypopigmented zone. A rare presentation of actinic lichen planus mimics melasma but have distinctive histopathologic picture in favour of actinic lichen planus. Herein, we report a 14-year-old boy who presented with a me...

Pigmented Contact dermatitis is a non-eczematous variant of contact dermatitis clinically characterised by reddish-brown to slate grey pigmentation in a reticulate pattern, usually without any active or preceding clinical dermatitis. A detailed history is essential to establish the temporal correlation of exposure to a possible sensitizer, which further helps in differentiating PCD from its clo...

BACKGROUND Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE We sought to provide clinicians with such a tool. METHODS A 2-gene classification method based on LINC00518 and preferentially expressed antigen in melanoma (PRAME) gene expression was...

isolation of pigmented t.violaceum from a patient with endothrix infection associated with the inflammatory and kerion symptoms and also isolation of the non- pigmented strain from another patient with non-inflammatory symptoms, led us to investigate the enzymic activities in both strains. most of the studies on dermatophyte compoxition have shown the relationship between proteolytic enzymes an...

(1) An early de-pigmented stage. (2) A later nodular stage. (3) A xanthoma-type of the disease in which there is a tendency towards fibrous tissue formation, and constriction of venules and subsequent dilatation. It is stated by these authors that the nodules appear in the place of de-pigmented patches. Generally speaking, cases of dermal leishmanoid come for treatment when both the nodules and...