results the present work figured out that the heterogeneity of the quasispecies of our local strains 4a was high showing up 15% diversity. this study also showed four glycosylation sites that play an important role in the entry of the virus and protein folding. besides, different epitpoes were identified in different regions of the e1 and e2 domains; a finding which would help in determining th...

peanut plants showing mottling, yellow and necrotic spots on leaves were collected from peanut fields in golestan province. electron microscopic studies revealed the presence of flexuous filamentous particles ca. 700 nm in length, which was suggestive of a potyvirus infection. healthy nicotiana benthamiana plants mechanically inoculated with sap from infected peanut plants showed mottling, down...

background and aims: rubella virus is a human pathogen that causes congenital rubella syndrome (crs) when infection occurs during early pregnancy. vaccination programs have been remarkably successful in controlling natural rubella infection and crs. moreover, ongoing surveillance for all cases of rubella and crs is a vital component of a prevention program. although the who recommends the use o...

avian pneumovirus (apv) causes turkey rhinotracheitis (trt) and swollen head syndrome (shs) of chickens, which is usually accompanied by secondary bacterial infections that increase mortality. in iran, some serological studies indicated that apv infection is endemic in commercial poultry industry. in this study we diagnosed apv genome molecularly in suspected broiler flock (4 weeks) in iran and...

background and aims: hdv is a defective satellite virus and classified in genus deltavirus. its disease is related and limited to hbv-infected patients. acute infection of delta agent occurs in two different patterns simultaneous infection with both hbv & hdv or super infection of chronically hbv infected patients that lead to more sever type of hepatitis. according to genetic diversity of geno...

the pb2 protein of influenza a viruses has been shown as host range determinant. in this study pb2gene of five h9n2 isolates from tehran province during the period of 1998-2001 were partially amplifiedand sequenced to do phylogenetic study. iranian isolates could be classified in eurasian lineage according totheir pb2 gene sequences. the pb2 genes of these isolates are different from those of m...

background and aims: avian metapneumovirus (ampv) is rna virus responsible for upper respiratory disease in poultry which is usually accompanied by secondary bacterial infections. in iran, some molecular and serological studies indicated that ampv infection occurred in commercial poultry industry. materials and methods: in this study ampv was molecularly identified and characterized in an affec...

background and aims: hemagglutinin (ha) protein of avian influenza (ai) plays an essential role in the virus pathogenicity. ai h9n2 subtype causes significant economic loss in broiler and layer in poultry farms in iran. ai viruses have a great involvement in evolutionary changes at nucleotide and amino acid levels and vaccines could induce faster rates of such changes. up-dated understanding of...

conclusions overall, results of present study were consistent with the data reported earlier base on 5’ ntr in iranian isolates and revealed genotype ir2 is major genotype in iranian hgv-positive patient. it means there are higher similarities between iranian and europe-usa in hgv ns3 gene. results nucleotide blast results emphasized that most similar sequences to ir ns3 sequences were those fr...

conclusions the prevalence of b. hominis in the study area was lower than that reported for most developed countries, and unlike in other countries in the middle east, st4 was the most prevalent subtype. results blastocystis hominis was found to have a prevalence of 3.33% in the study population. there was no significant association of blastocystis infection with age (p = 0.3) or gender (p = 0....