BACKGROUND There have been conflicting data in literature about the value of Phyllanthus amarus in treating hepatitis B virus-related disorders. AIM To evaluate the role of Phyllanthus amarus in eradication of the virus in hepatitis B carriers. METHODS Phyllanthus amarus was administered to 30 asymptomatic carriers of hepatitis B surface antigen (HBsAg) in a dosage of 250 to 500 mg thrice d...

The effects of methanol extract of Phyllanthus amarus on different phases of in lammation were examined. Investigations were performed using different phlogistic agents-induced paw e ema, carrageenan-induced airpouch inflammation and cotton pellet granuloma in rats. Methanol extract of Phyllanthus amarus significantly inhibited carrageenan, bradykinin, serotonin and prostaglandin E1-induced paw...

In search of the effective and standardized hepatoprotective combination therapy, silymarin and standardized extract of Phyllanthus amarus has been evaluated against CCl(4)-induced hepatotoxicity in rats. Eight groups of rats were used. The animals of group A served as normal and were given only vehicle. The animals of group B served as toxin control and were administered with CCl(4) (50% solut...

Herbs have always formed an integral part of human health and are used in the treatment of several human diseases. One of such species which have wide patronage of use is Phyllanthus amarus. This herb is in traditional medicine for more than 3,000 years. The plant has also served as lead for several experimental investigations that explored its phytochemical constituents and pharmacological use...

Phyllanthus amarus has been proven to exhibit chondroprotection. Regarding the morphological similarities among Phyllanthus species, we were attracted to evaluate the chondroprotective potential of Phyllanthus species including P. amarus obtained from Chiang Mai and Phuket, Phyllanthus urinaria L., Phyllanthus urinaria subsp. chamaepeuce, Phyllanthus debilis, and Phyllanthus airy-shawii using i...

The present study was aimed at evaluating the antifertility effect of phyllanthus amarus extract in male wistar rats. The body and organ weights, cauda epididymal sperm parameters, serum levels of male reproductive hormones and fructose were assessed. Daily oral doses of the extract were administered to each animal in three different test groups for 28 consecutive days. Results show significant...

The effects of the methanol extracts of the leaves of Phyllanthus amarus on the sperm parameters of male Guinea pigs were investigated. The effects of Vitamin E on the sperm parameters were also investigated and compared to that of Phyllanthus amarus. The phytochemical screening of the leaves of Phyllanthus amarus was also carried out. The methanol extract of the Phyllanthus amarus leaf (50-200...

General phytochemical screening of Phyllanthus amarus (Euphorbiaceae) revealed the presence of Saponin, tannins, glycoside and alkaloids etc. The aim of this study is to identify and characterize the bioactive principle from the plant. It has wide folk medicinal uses. The isolation and characterization of Phytoconstituents was done from the methanolic extract by the gradient fractionation metho...

Histological studies of the effects of oral administration of aqueous extract of Phyllanthus amarus commonly used in ethno medical practice in Africa for the management of various ailments such as kidney stones, dysentery, jaundice, diarrhoea and urogenital diseases on the kidney of adult Wistar rats were carefully studied. Rats of both sexes (n=24), average weight of 260g were randomly assigne...

In the present study, leaves of Ocimum sanctum, Azadirachta indica and Phyllanthus amarus were collected and the collected leaves were shade dried and powdered by hand crushing. The preparations of different leaves extract was done through modified method. Three different solvents viz., methanol, chloroform and ethyl acetate were used to study the antimicrobial activity of herbal plants. Disc d...