we design a novel nano-ring resonator using two-dimensional photonic crystal (2d-phc), for bio-sensing applications. the structure of biosensor is created by two-curve-shaped ring resonator which sandwiched by two waveguides. these are configured by removing one row of air holes. the refractive index of sensing hole is changed by binding an analyte. hence, intensity of the transmission spectrum...

Utilizing its integrated camera as a spectrometer, we demonstrate the use of a smartphone as the detection instrument for a label-free photonic crystal biosensor. A custom-designed cradle holds the smartphone in fixed alignment with optical components, allowing for accurate and repeatable measurements of shifts in the resonant wavelength of the sensor. Externally provided broadband light incide...

Utilizing its integrated camera as a spectrometer, we demonstrate the use of a smartphone as the detection instrument for a label-free photonic crystal biosensor. A custom-designed cradle holds the smartphone in fixed alignment with optical components, allowing for accurate and repeatable measurements of shifts in the resonant wavelength of the sensor. Externally provided broadband light incide...

We have developed a novel biosensor for kinases that is based on a kinase-responsive polymer hydrogel, which enables label-free screening of kinase activity via changes in optical properties. The hydrogel is specifically designed to swell reversibly upon phosphorylation of a target peptide, triggering a change in optical diffraction from a crystalline colloidal array of particles impregnated in...

A label-free optical biosensor based on a one-dimensional photonic crystal microring resonator with enhanced light-matter interaction is demonstrated. More than a 2-fold improvement in volumetric and surface sensing sensitivity is achieved compared to conventional microring sensors. The experimental bulk detection sensitivity is ~248nm/RIU and label-free detection of DNA and proteins is reporte...

A novel assembled biosensor was prepared for detecting 16S rRNA, a small-size persistent specific for Actinobacteria. The mechanism of the porous silicon (PS) photonic crystal biosensor is based on the fluorescence resonance energy transfer (FRET) between quantum dots (QDs) and gold nanoparticles (AuNPs) through DNA hybridization, where QDs act as an emission donor and AuNPs serve as a fluoresc...

In this paper, homogeneous, wavelength shift biosensor is designed for sensing the protein concentration using two dimensional Photonic Crystal Ring Resonator (PCRR). The sensor is designed to monitor the protein concentration from 0% to 100%. The proposed sensor is composed of periodic Si rods embedded in an air host with a circular PCRR that is placed between the inline quasi waveguides. It i...