The decoction of Pheretima aspergillum is used as a traditional medicine for treatment of asthma in China with a long clinical history. The aim of the study was to investigate the anti-asthma activities of an active components group obtained from the decoction of Pheretima aspergillum in histamine and ovalubumin induced asthma guinea pigs. The incubation period of asthma, serum IFN-γ, IL-4 and ...

The decoction of Pheretima aspergillum is used as a traditional medicine for treatment of asthma in China with a long clinical history. The aim of the study was to investigate the anti-asthma activities of an active components group obtained from the decoction of Pheretima aspergillum in histamine and ovalubumin induced asthma guinea pigs. The incubation period of asthma, serum IFN-γ, IL-4 and ...

Cancer-related wounds are still one of the healing challenges that faced by various health practitioners, where these often unsightly and associated with foul odor, drainage, bleeding. Wounds caused malignant tumors have a wide range symptoms severity, thus there is no treatment has been demonstrated to be able relieve them effectively. The use wound dressings, which antibacterial advantages he...

BACKGROUND Guang-Pheretima, which is originated from Pheretima aspergillum, has been documented in academic Chinese herbal studies for nearly 2000 years for its prominent treating effects of various inflammatory diseases such as asthma, cough and fever. However, the anti-inflammatory activity and mechanism of Guang-Pheretima has been rarely reported. Hence, we investigated the inhibitory effect...

Objective: To evaluate the anthelmintic activity of Artemisia indica. Methods: In the present investigation, the in vitro anthelminthic activity of chloroform, methanol and aqueous extracts of Artemisia indica was carried out against Indian adult earthworm Pheretima posthuma. Piperazine citrate was used as the standard reference. Five different concentrations (1.25, 2.5, 3.75, 5.0 and 6.25 mg/m...

A simple and rapid ultra-performance liquid chromatography-electrospray ionization mass spectrometry method for the simultaneous determination of thirteen free fatty acids (FFAs) in Pheretima has been developed and validated. Measurements for each FFA were linear over a wide range (0.05–3.95 μg mL) with good correlation coefficients (>0.99). The limit of detection and limit of quantification fo...

We investigated the curative effect of Pheretima aspergillum (earthworm, PA) on rats with middle cerebral artery occlusion (MCAo). The MCAo-induced cerebral infarction was established and its underlying mechanisms by counting the infarction areas and evaluating the rats' neurological status. Immunostaining was used to test the expression of NeuN, and glial fibrillary acidic (GFAP), S100B, and b...

Different extracts of L. cylindrica were taken for anthelmintic activity against Indian earthworm Pheretima posthuma. Two concentrations (50 and 100 mg/ml) of various extracts were tested and results were expressed in terms of time for paralysis and time for death of worms. Albendazole (20 mg/ml) was used as reference standard and carboxy methyl cellulose (0.5%) as a control group. Dose depende...

Alcohol and aqueous extracts from the leaves of Argemone mexicana were investigated for their anthelmintic activity against Pheretima posthuma and Ascardia galli. Five concentrations (6.25, 12.5, 25, 50 and 100 mg/ml) of each extracts were studied in activity, which involved the determination of time of paralysis and time of death of the worms. Both the extracts exhibited significant anthelmint...