some otolaryngologists administer topical phenylephrine for bleeding control in adenoidectomy surgery. absorption of this drug from surgical site can lead to increase in blood pressure due to vasoconstriction and then bradycardia related to baroreceptore reflex.  our case was an intraoperative arrest of a 9-yrs-old girl related to administration of topical phenylephrine during adenoidectomy how...

Some otolaryngologists administer topical phenylephrine for bleeding control in adenoidectomy surgery. Absorption of this drug from surgical site can lead to increase in blood pressure due to vasoconstriction and then bradycardia related to baroreceptore reflex.  Our case was an intraoperative arrest of a 9-yrs-old girl related to administration of topical phenylephrine during adenoidectomy how...

Background: Spinal anesthesia is an accepted technique in elective cesarean sections. However, hypotension, resulted from sympathectomy is a common problem, especially in pregnant women. Prevention of this complication by sympathomimetic agents is of potential clinical significance. The aim of this study is to compare the effect of prophylactic infusion of Phenylephrine versus Ephedrine in the ...

BackgroundImmunosuppression after surgery is associated with postoperative complications, mediated in part by catecholamines that exert anti-inflammatory effects via the β-adrenergic receptor. Phenylephrine, generally regarded as a selective α-adrenergic agonist, frequently used to treat perioperative hypotension. However, phenylephrine may impair host defence through affinity.MethodsHuman leuk...

This work includes the development of two spectrophotometric methods which are sensitive, accurate, stable, and has good recovery for determination phenylephrine-HCl as free form in pharmaceutical preparations. In method (A), phenylephrine is oxidized by potassium permanganate a basic solution sodium hydroxide bluish-green color resulting manganate (MnO 42- ) measured at wavelength 610 nm, line...

The Au–Bi binary system electrodeposited on the surface of a glassy carbon electrode exhibits catalytic activity during electrooxidation phenylephrine, paracetamol, and caffeine that enhances peak currents decreases overvoltage in oxidation organic compounds. potential difference between peaks modified is 400 mV for phenylephrine paracetamol 300 caffeine, respectively. possibility simultaneous ...

background: alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused rat lung. in this study, we investigated the effect of sustained hypoxic ventilation o...

background: spinal anesthesia is an accepted technique in elective cesarean sections. however, hypotension, resulted from sympathectomy is a common problem, especially in pregnant women. prevention of this complication by sympathomimetic agents is of potential clinical significance. the aim of this study is to compare the effect of prophylactic infusion of phenylephrine versus ephedrine in the ...

Background: Alveolar hypoxia induces monophasic pulmonary vasoconstriction in vivo, biphasic vasoconstriction in the isolated pulmonary artery, and controversial responses in the isolated perfused lung. Pulmonary vascular responses to sustained alveolar hypoxia have not been addressed in the isolated perfused rat lung. In this study, we investigated the effect of sustained hypoxic ventilation o...

it has been shown in some investigations that cardiovascular events are the main causes of death in hemodialysis patients. the exact etiology is unknown but some of the articles have reported a relation between aluminium ions in the dialysis solution and cardiovascular disorders. to determine the probable effect of aluminium on vasculature function, in vitro effects of aluminium ion on vasocons...