The International Mouse Phenotyping Consortium (IMPC) portal allows you to search for phenotypes, disease models and knockout mouse strains for your gene of interest. This course will show you how to use the IMPC portal and what data is available. Learn what the IMPC is and what you can do with the portal Determine whether there are phenotypes and potential disease models for your gene of inter...

ulcerative colitis (uc) is a nonspecific acute and chronic inflammatory bowel disease that diffusely involves the colonic mucosa. the etiology of uc has not yet been elucidated fully. however, many studies have found that immunologic disorders may play a role in the pathogenesis of uc. in addition, due to an increased frequency of uc in families, especially an increased monozygotic compared wit...

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On-going automation in plant phenotyping has led to an increasing amount of measurement data, which is often managed by specialized, rarely interconnected systems with custom hardand software. Experiment and analysis scenarios across different systems and the setup of new systems quickly get expensive and tedious. Therefore, we propose a distributed information system, Phenomis, for managing ph...

introduction: acute leukemia is the most common malignancy in children and acute lymphoblastic leukemia (all) accounts for 75% of acute leukemia cases. new treatment protocols have resulted in complete remission rates up to nearly 100% in children with acute lymphoblastic leukemia. today, one of the most important prognostic factors in acute lymphoblastic leukemia is intensity of the treatment....

contamination sites of pseudomonas fluorescenswere traced in the production line for milk pasteurization in a large dairy plant in shiraz, iran. samples of raw and pasteurized milk were collected at six sites along the line. all milk samples were incubated at 7°c until the aerobic plate count had reached 10 6 -10 7 cfu ml-1. colonies were picked randomly and identified. no growth of gram negati...

The widespread usage of electronic health records (EHRs) for clinical research has produced multiple electronic phenotyping approaches. Methods for electronic phenotyping range from those needing extensive specialized medical expert supervision to those based on semi-supervised learning techniques. We present Automated PHenotype Routine for Observational Definition, Identification, Training and...

Over a period of three years we determined haptoglobin levels by single radial immunodiffusion (RID) and the haptoglobin phenotype in over 1700 samples of patients suspected of a haemolytic disease. As haptoglobin phenotyping is rather laborious and therefore an expensive method, we re-evaluated the diagnostic need for phenotyping. From our reference values for the respective phenotypes of hapt...

We propose an approach to automated 3D reconstruction of plant architecture followed by a precise derivation of phenotypic traits. We applied and evaluated our approach within a grapevine phenotyping project. The reconstruction results and the derived phenotypic traits could be shown to be in line with given ground truth data. Furthermore, our approach that combines a generative modelling of pl...

BACKGROUND AND OBJECTIVE Dried blood spot (DBS) sampling has gained wide interest in bioanalysis during the last decade and has already been successfully applied in pharmacokinetic and phenotyping studies. However, all of the available phenotyping studies used small datasets and did not include a systematic evaluation of DBS-specific parameters. The latter is important since several of these fa...