Pharmaceutical contamination of shallow groundwater is a substantial concern in effluent-dominated streams, due to high aqueous mobility, designed bioactivity, and effluent-driven hydraulic gradients. In October and December 2012, effluent contributed approximately 99% and 71%, respectively, to downstream flow in Fourmile Creek, Iowa, USA. Strong hydrologic connectivity was observed between sur...

Pharmaceutical and personal care products (PPCPs) industries suffer inadequate effluent treatment due to the presence of recalcitrant substances, insufficient carbon source and nutrients. Biodegradation is the ability of microorganisms to metabolize pollutants in soil, sediment and water environment. There is great awareness in the positive impact that microorganisms play in protecting environm...

There is scarcity of information on the possible mechanisms of pharmaceutical effluent induced genotoxicity and systemic toxicity. This study investigated the genotoxicity and systemic toxicity of a pharmaceutical effluent in Wistar rats. Rats were orally treated with 5-50% concentrations of the effluent for 28 days. At post-exposure, blood, liver, kidney and bone marrow cells were examined for...

Two bacterial strains were isolated from pharmaceutical effluents discharged soil. The samples were identified as Klebsiella pneumonia and Pseudomonas aeruginosa the biological degradation was carried on two bacterial isolates separately added to pharmaceutical effluent water. After proper interval were analysed the physic chemical parameters such as pH, Turbidity, Chemical oxygen demand (COD),...

Facilities involved in the manufacture of pharmaceutical products are an under-investigated source of pharmaceuticals to the environment. Between 2004 and 2009, 35 to 38 effluent samples were collected from each of three wastewater treatment plants (WWTPs) in New York and analyzed for seven pharmaceuticals including opioids and muscle relaxants. Two WWTPs (NY2 and NY3) receive substantial flows...

The occurrence and estimated concentration of twenty illicit and therapeutic pharmaceuticals and metabolites in surface waters influenced by wastewater treatment plant (WWTP) discharge and in wastewater effluents in Nebraska were determined using Polar Organic Chemical Integrative Samplers (POCIS). Samplers were installed in rivers upstream and downstream of treated WWTP discharge at four sites...

Pharmaceutical industries are among the major contributors to industrial waste. Their effluents when wrongly handled and disposed of endanger both human and environmental health. In this study, we investigated the potential genotoxicity of a pharmaceutical effluent, by using the Allium cepa, mouse- sperm morphology, bone marrow chromosome aberration (CA) and micronucleus (MN) assays. Some of th...

This paper presents the genotoxic effect of effluent from a pharmaceutical plant in Ota, Ogun state, Nigeria using the rat bone-marrow metaphase chromosome assay. The effluent was examined for some standard physical and chemical properties. Rats were intraperitoneally exposed to 1%, 5%, 10%, 25% and 50% (v/v, effluent/distilled water) concentrations of the effluent for 48 hr. Distilled water an...

Low levels of active pharmaceutical ingredients (APIs) turning up in natural waterways and drinking water supplies are coming under increasing scrutiny for their potential health effects on people and wildlife. Human waste has been identified as the main source of these pharmaceuticals, along with the common practice of flushing unused medications down the toilet. Now, a new study by the U.S. G...

To develop a better understanding of the issues and best practices related to the use of treated effluent to help maintain river flows and habitat, the Conservancy commissioned a study to summarize the state of the science. The use of treated wastewater effluent is becoming a more prominent factor in Arizona’s overall water management strategy. Treated effluent contains a wide array of chemical...