BACKGROUND The choice of tetanus prophylaxis for patients with wounds depends on obtaining their vaccination history, which has been demonstrated to be unreliable. Use of a rapid immunoassay (Tétanos Quick Stick, the TQS), combined with knowledge of certain demographic characteristics, may improve the evaluation of tetanus immunity and thus help to avoid inadequate prophylactic measures and red...

Diagnosis of tetanus immunization status by medical interview of patients with wounds is poor. Many protected patients receive unnecessary vaccine or immunoglobulin, and unprotected patients may receive nothing. The aim of this study is to evaluate the feasibility and accuracy of the Tetanos Quick Stick (TQS) rapid finger prick stick test in the emergency department for determining immunization...

Acetylcholine activates nicotinic acetylcholine receptors (nAChRs) by binding to an extracellular site located at the interface of two adjacent subunits. In contrast, recent studies have provided evidence that positive allosteric modulators (PAMs) such as TQS (4-(naphthalen-2-yl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide) and allosteric agonists such as 4BP-TQS (4-(4-bromophe...

INTRODUCTION Based on the existing studies, measuring serum level of immunoglobulin for making decisions regarding prescription of tetanus prophylaxis seems logical and cost effective. Therefore, the present study was done with the aim of evaluating the diagnostic accuracy of tetanus quick stick (TQS) in comparison with ELISA method in this regard. METHODS The present diagnostic accuracy stud...

This paper presents Timed Quorum System (TQS), a new quorum system especially suited for large-scale and dynamic systems. TQS requires that two quorums intersect with high probability if they are used in the same small period of time. It proposed an algorithm that implements TQS and that verifies probabilistic atomicity: a consistency criterion that requires each operation to respect atomicity ...

This paper presents Timed Quorum System (TQS), a new quorum system especially suited for large-scale and dynamic systems. TQS requires that two quorums intersect with high probability if they are used in the same small period of time. It proposed an algorithm that implements TQS and that verifies probabilistic atomicity: a consistency criterion that requires each operation to respect atomicity ...

Conventional nicotinic acetylcholine receptor (nAChR) agonists, such as acetylcholine, act at an extracellular "orthosteric" binding site located at the interface between two adjacent subunits. Here, we present evidence of potent activation of α7 nAChRs via an allosteric transmembrane site. Previous studies have identified a series of nAChR-positive allosteric modulators (PAMs) that lack agonis...

Introduction: Teaching Qualifications (TQs) have been implemented in University Medical Centers, but their relation to teachers’ motivation for medical teaching is unknown. Because teacher motivation influences important outcomes, it is crucial to study how TQs are related to promoting teacher motivation, by fulfilling the basic needs of feeling autonomous, competent, and related towards medica...

This paper presents Timed Quorum System (TQS), a quorum system for large-scale and dynamic systems. TQS provides guarantees that two quorums, accessed at instances of time that are close together, intersect with high probability. We present an algorithm that implements TQS at its core and that provides operations that respect atomicity with high probability. This TQS implementation has quorums ...

Seroepidemiological studies of tetanus in Africans have focused mainly on adults especially pregnant women and data on children are scarcely reported. We investigated the seroprevalence of protective immunity level, determined risk factors for non-protection against tetanus, and evaluated the performance of Tetanos Quick Stick(®) (TQS) among hospitalized children aged 1-9 years in Nigeria. Bloo...