Abstract: Minoxidil, a pyrimidine derivative (2, 4-diamino-6-piperidinopyrimidine-3-oxide) is the only topical medical treatment with proven efficacy for the treatment of Androgenetic alopecia that shown low skin penetration and bioavailability. The main aim of this research was to investigate the effect of some permeation enhancers on the in vitro skin permeability of minoxidil . Minoxid...

Mixed matrix membranes (MMMs) are attracting significant interest for pervaporation and gas separation applications. To better comprehend the impact of filler particles within polymer matrices, the species permeation mass transport was theoretically studied by numerical simulation using finite differences. The Fick’s second law of diffusion was solved for a three-dimensional MMM to obtain the c...

comnode classification within membrane residue curves (m-rcms) currently hinges on lyapunov’s theorem and therefore the computation of mathematically complex eigenvalues. this paper presents an alternative criterion for the classification of nodes within m-rcms based on the total membrane flux at node compositions. this paper demonstrates that for a system exhibiting simple permeation behaviour...

A model that relates hydraulic permeability to water flux and to gradients in pressure potential and solute potential was tested using soybean (Glycine max) plants. Water flux was varied by additions of polyethylene glycol 6,000 around one portion of a divided root system and by changing the light intensity and CO(2) concentration around the plants. The data are compatible with the model only i...

Paracellular permeability and absorptive water flux across the intestine of the euryhaline killifish were investigated using in vitro gut sac preparations from seawater- and freshwater-acclimated animals. The permeability of polyethylene glycol (PEG), a well-established paracellular probe, was measured using trace amounts of radiolabelled oligomers of three different molecular sizes (PEG-400, P...

In this research thin film heterogeneous cation exchange membrane was prepared by interfacial polymerization of polyacrylic acid-co-iron nickel oxide nanoparticle son PVC based substrate. Spectra analysis confirmed graft polymerization conclusively. The SEM images showed that polymerized layer covers the membranes by simple gel network entanglement. Results exhibited that membrane water content...

comNode classification within Membrane Residue Curves (M-RCMs) currently hinges on Lyapunov’s Theorem and therefore the computation of mathematically complex eigenvalues. This paper presents an alternative criterion for the classification of nodes within M-RCMs based on the total membrane flux at node compositions. This paper demonstrates that for a system exhibiting simple permeation behaviour...

A high flux thin-film nanocomposite membrane epoxy/ zeolite NaA nanocomposite films prepared by using ultrasonic mixing and spin coating. The synthesized nanocomposites film was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM), thermal gravity analysis (TGA), and FTIR spectroscopy. Water softener and water flux characteristics of the epoxy/ zeolite NaA nanocomposite ...

Polyethersulfone (PES) based nanocomposite nanofiltration membrane was prepared by immersion precipitation method and casting solution technique using  poly (acrylic acid) grafted-iron oxide nanoparticles (Fe3O4) as hydrophilic filler additives. For this purpose, iron oxide nanoparticles were modified by in situ polymerization of acrylic acid in aqueous solution by potassium persulfate as initi...

We investigated the pathways for low density lipoprotein (LDL) transport across an endothelial barrier in individually perfused microvessels before and after an increase in permeability. The divalent cation ionophore A23187 (5 microM) was used to increase microvessel permeability. LDL permeability coefficients (PsLDL) were measured using quantitative fluorescence microscopy. In the control stat...