objectives microscopy of giemsa-stained thick and thin peripheral blood smear (pbs) remains as the standard laboratory method for the diagnosis of symptomatic malaria. this study was done to compare pbs with polymerase chain reaction (pcr) method for detecting asymptomatic malaria parasitemia. patients and method blood samples were collected from 900 asymptomatic school children between 7-11 ye...

objective: elevated nucleated red blood cell (nrbc) count is introduced as a potential marker of intra-uterine growth restriction (iugr). to investigate the probable association regardless of any known underlying disease, we aimed to study disturbances in nrbc count in infants experiencing idiopathic iugr. materials and methods: twenty three infants regarded iugr without any known cause were ch...

cytomegalovirus is the most important pathogen affecting transplant recipients and causing significant morbidity and morbidity. the prevalence of cmv  infections in transplant recipient varies from country to country.  the aim of this study was to determine the prognostic value of pcr assay for cmv  detection in patients before keratoplasty.  a total of 23 patient samples enrolled in this study...

background: atherosclerosis, a chronic inflammatory disease of the vessel wall is characterized by local and systemic immune responses to a variety of antigens. oxidized low-density lipoprotein (oxldl) is considered as an important determining factor in the pathogenesis of atherosclerosis. objective: the purpose of this study was to investigate the degree of peripheral blood mononuclear cells (...

background: dendritic cells (dcs) are the most potent stimulators of primary t cell responses and play a key role in immune reactions after stem cell transplantation. very little is known about the cord blood (cb) dendritic cells and their potential involvement in the low incidence and lower severity of acute graft-versus-host disease after cb transplantation.   objectives: the aim of this stud...

background lichen planus is a disease with unknown etiology that affects the skin and the mucous membranes. immune dysregulation in the pathogenesis of oral lichen planus (olp) is well-known phenomenon. objectives in this study, we compared the levels of the peripheral blood t lymphocytes between patients with olp and control group. patients and methods in this study, 32 and 16 patients respect...

background : an elevation in the mean percentages of the gamma delta t lymphocytes per total t cells in the epithelium of the small intestine has a diagnostic value for celiac disease.  this study aimed to measure the percentages of the peripheral blood gamma delta t lymphocytes in the adults' celiac disease and healthy controls. materials and methods: in this case-control study the absolute nu...

introduction: neuroblastoma is the most common extracranial solid tumor in children, accounting for 8% to 10% of all childhood cancers. significantly, autologous transplantation appeared to have the largest impact on survival for the high risk subset of patients, such as those with n-myc amplified metastatic disease diagnosed after age 2 years. patients and methods: this study includes high ris...

peripheral blood stem cell transplantation (pbsct) is an effective treatment for hematological malignancies. mobilization of peripheral blood progenitor cells performs in different ways among transplantation centers. forceful mobilization schedules are comprised of growth factor alone, chemotherapy along with growth factor and also, a newly combination of novel agent such as plerixafor with any...

introduction: multiple sclerosis (ms) is generally known as a manageable but not yet curable autoimmune disease affecting central nervous system. a potential therapeutic approach should possess several properties: prevent immune system from damaging the brain and spinal cord, promote differentiation of oligodendrocyte progenitor cells (opcs) into mature oligodendrocytes to produce myelin, preve...