1 Center for Language and Cognition Groningen, University of Groningen, Groningen, Netherlands, 2 Department of Experimental Psychology, University of Groningen, Groningen, Netherlands, 3 Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom, 4 College of Information Sciences and Technology, The Pennsylvania State University, State College, PA, United States, 5 Dep...

    Motor units (MUs) reflect the function of the central nervous motor system. Thus, the estimated MU number is a good option to investigate the functional movement disorder in the Parkinson’s disease (PD). The purpose of this study was to compare the estimated MUs number in the medial gastrocnemius (MG) muscle of the normal rats and those with the Parkinsonism. The MG muscle of two age-matche...

parkinsonism is used to describe a syndrome manifested by any combination of six cardinal features: tremor at rest, rigidity, bradykinesia, loss of postural reflexes, flexed posture and the freezing. decreased dopaminergic neurotransmission in the basal ganglia is the core biochemical pathology in parkinsonism. hereditary parkinsonism includes various heredodegenerative diseases such as hallerv...

a 49 year old woman diagnosed as a cervical cancer patient, after receiving appropriate treatment experienced metastasis in her abdominopelvic cavity. after aggressive management, she was well for a while. however, she developed to a poor condition consisting of urologic, gastroenterological, hematologic and neurologic problems just in a short time. in the course of hospital she presented one s...

Introduction: High levels of homocysteine (Hcy) might accelerate dopaminergic cell death through oxidative stress and excitotoxicity. Folate plays an important role in the control of plasma levels of Hcy. In this study, effect of supplementation with folic acid on the 6-hydroxydopamine (6-OHDA)-induced Parkinsonism in rat and also serum level of Hcy was investigated. Methods: Rats were fed ...

discussion neurobrucellosis is a rare presentation of brucellosis and should be considered when neurological problems cannot be explained by other etiology especially in endemic areas. introduction brucellosis is a zoonotic infection with high distribution all over the world and has many clinical manifestations, one of which is neurobrucellosis (nb). case presentation our case was a 78-year-old...

motor units (mus) reflect the function of the central nervous motor system. thus, the estimated mu number is a good option to investigate the functional movement disorder in the parkinson’s disease (pd). the purpose of this study was to compare the estimated mus number in the medial gastrocnemius (mg) muscle of the normal rats and those with the parkinsonism. the mg muscle of two age-matched gr...

Infantile- and childhood-onset parkinsonism is mainly due to genetic alterations an exceedingly rare condition, unlike Parkinson's disease (PD), which one of the most common neurologic disorders in adulthood. The clinical characterization during early stages neuromotor development controversial lack consensus regarding criteria PD or immature brain. classification here proposed based on a revie...

Objective(s): Parkinson's disease (PD) is a progressive neurological disorder associated with motor disabilities and cognitive dysfunction as well. Evidence indicates that PD occurs less frequently in women than men, confirming a role for steroid hormones in protection of dopaminergic nigrostriatal neurons. It is reported that soy genistein, an estrogen agonist phytoestrogen, display neuroprote...

Introduction: Transplantation of embryonic ventral mesencephalic (VM) dopamine neurons into the striatum is a currently explored therapeutic strategy for treatment of patients with patients with Parkinson's disease (PD). However, this strategy has been limited with poor cell survival, generally ranging from 5-20%. In this study, we investigated the effect of potassium channel blocker of tetr...