Ischemic stroke is the major killer and is the most important cause of morbidity and mortality world wide. The increasing incidence is due to hypertension, stress of life,obesity, lack of exercise and other factors. We attempted to determine an independent association of paraoxanase with ischemic stroke patients. The lipid profile and serum paraoxanase were investigated in 100 ischemic stroke p...

Stroke is the leading cause of mortality and long term disability among adults in industrialized countries. Oxidative stress is an independent risk actor by inducing production of oxygen free radicals in ischemic stroke. Because a relationship may be associated between ox-ldl and paraoxanase, the aim of this study was to investigate the association between ox-ldl and paraoxanase in ischemic str...

OBJECTIVES Paraoxanase 1 (PON1) plays a protective role against the oxidative modification of plasma lipoproteins and hydrolyzes lipid peroxides in human atherosclerotic lesions. Cumin is the dried seed of the herb Cuminumcyminum that is known as Zeera in Iran. Cumin seeds contain flavonoids which are now generally recognized to have antioxidant activity and improve the antioxidant system. So, ...

Objectives: To investigate the alterations in the oxidant-antioxidant balance in patients with acute ischaemic stroke, and to locate any correlation between oxidant/antioxidant parameters and the National Institute of Health Stroke Scale. Methods: The case-control study was conducted at the Neurology Department of Dicle University Medical Faculty, Diyarbakir, Turkey, from June 2010 to June 2011...

BACKGROUND AND OBJECTIVES The aim of this study was to investigate serum paraoxanase-1 (PON) activity, total oxidant status (TOS), total antioxidant status (TAS), and the oxidative stress index (OSI) in tinnitus; and to compare the results with data from healthy subjects. SUBJECTS AND METHODS A total of 114 subjects-54 patients with tinnitus and 60 healthy controls were enrolled in this study...

Stroke is the leading cause of mortality and morbidity world wide, particularly in the elderly. Oxidative stress is an independent risk factor by inducing production of oxygen free radicals in ischemic stroke. Because a relationship may be hypothesized between paraoxanase (PON) and malondialdehyde(MDA),the aim of this study was to investigate the relationship between PON and oxidative stress wi...