Background: Discoid lupus erythematosus (DLE) is a variety of lupus disease characterized with sticky thick scaces telangiectasia and follicular plugging. Objectives: To determine the relative frequency of clinical, paraclinical and pathological findings in patients with DLE. Patients and Methods: The clinical, Paraclinical and pathological findings in 50 biopsy proven patients with DLE referre...

Abdominal cocoon is a rare disease which causes small-bowel obstruction that is characterized by a thick, fibrotic and cocoon-like membrane encapsulating total or partially the small bowel1,2,3. Its etiology remains unknown4,5. Surgical management is the treatment of choice1. In this report, it is described a young patient with abdominal cocoon who presented clinical signs and paraclinical find...

Following empirical studies on schizophrenic and bipolar vulnerabilities, research on endophenotypes knows a recent major development. Two main definitions of early and stable vulnerability markers may be distinguished. First, a strict definition of endophenotype relies on a quantifiable and mainly paraclinical measure (e.g., biological data, electrophysiology or functional imaging). Second, a ...

We describe a patient with a combination of dystonic and parkinsonian signs. Paraclinical studies revealed a mutation in the GTP cyclohydrolase I gene (GCH1) and a decrease in [123I]-N-omega-fluoropropyl-2beta-carbomethoxy-3beta-(4-iodophenyl) nortropane (123I-FP-CIT) binding ratios indicative of Parkinson's disease. We conclude that the patient probably suffers from a variant of dopa-responsiv...

Dear Editor I read with great interest the case report titled “Periumbilical pain with radiation to both legs following tarantula bite; a case report” published in Emergency journal (1). The authors introduce a male patient presenting with periumbilical pain radiating to both legs. They performed paraclinical evaluations to rule out large vessel insult and herniated disk; however, he discharged...

Intracranial hemorrhage is a rare and fatal presentation of leptospirosis. In this paper we present the case of a 51-year-old male farmer who lives in northern Iran. He came to our hospital with a severe headache. A paraclinical evaluation showed clear signs of thrombocytopenia, and a brain MRI revealed left temporoparietal hemorrhage. Our preliminary diagnosis was Leptospirosis, and after 26 d...

Recently, many cases of autoimmune limbic encephalitis with positive GAD65 (glutamic acid decarboxylase) antibodies have been described in the scientific literature. However, it remains an understudied topic of great relevance to practicing neurologists. Thus, we report here a review of published cases, in English, of autoimmune limbic encephalitis with this type of antibodies, focusing on pres...

purpose: to report the clinical, paraclinical and histopathologic features of eyelid mass lesions in a patient with tuberous sclerosis. case report: a 14 year old boy with a slowly progressive right upper lid mass and history of seizures, mental retardation and multiple skin lesions on the face and body was referred to labbafinejad medical center. cortical tubers and subepandimal nodules were r...

Headache syndromes can be associated with focal neurological symptoms or signs. Good knowledge of primary headaches, a detailed history and a thorough clinical examination are prerequisites for their differential diagnosis. The neurological symptoms produced by the migraine aura are the most characteristic and recognisable. However, structural lesions, such as vascular malformations, can produc...

Omental torsion is caused by the rotation of the greater omentum on its axis which may lead to tissue infarction and necrosis. It is a rare cause of acute abdomen. Signs, symptoms and paraclinical data are not specific. The patients usually undergo laparotomy for acute abdomen of poorly defined origin. High index of suspicious is required for the diagnosis of this entity. The diagnosis is usual...