نتایج جستجو برای: PHL-C

تعداد نتایج: 1056918  

Bahram Abedi Ebrahim Ganji Moghadam Gholamhosein Davari Nejad Zohreh Hoshyar

PHL-C is one of the dwarf sweet cherry rootstocks which is a hybrid between P. avium L. × P. cerasus L. Direct rooting of sweet cherry rootstocks is difficult which can be solved by using in vitro propagation. Transfer of plantlets from in vitro to ex vitro limit the use of micro propagation, because of weak root systems and low survival rates. This study was conducted in order to select the be...

Journal: :Journal of immunology 2007
Kerstin Westritschnig Birgit Linhart Margarete Focke-Tejkl Tea Pavkov Walter Keller Tanja Ball Adriano Mari Arnulf Hartl Angelika Stöcklinger Sandra Scheiblhofer Josef Thalhamer Fatima Ferreira Stefan Vieths Lothar Vogel Alexandra Böhm Peter Valent Rudolf Valenta

Profilins are highly cross-reactive allergens in pollens and plant food. In a paradigmatic approach, the cDNA coding for timothy grass pollen profilin, Phl p 12, was used as a template to develop a new strategy for engineering an allergy vaccine with low IgE reactivity. Non-IgE-reactive fragments of Phl p 12 were identified by synthetic peptide chemistry and restructured (rs) as a new molecule,...

2014
Christoph Madritsch Elisabeth Gadermaier Christian Lupinek Rudolf Valenta Flicker Sabine

The timothy grass pollen allergen Phl p 1 belongs to the group 1 of highly cross-reactive grass pollen allergens with a molecular mass of ∼25-30 kDa. Group 1 allergens are recognized by >95% of grass pollen allergic patients. We investigated the IgE recognition of Phl p 1 using allergen-specific IgE-derived single-chain variable Ab fragments (IgE-ScFvs) isolated from a combinatorial library con...

2013
Ulrike Baranyi Martina Gattringer Andreas M Farkas Karin Hock Nina Pilat John Iacomini Rudolf Valenta Thomas Wekerle

The transplantation of allergens (e.g. Phl p 5 or Bet v 1) expressed on BM cells as membrane-anchored full-length proteins leads to permanent tolerance at the T-cell, B-cell, and effector-cell levels. Since the exposure of complete allergens bears the risk of inducing anaphylaxis, we investigated here whether expression of Phl p 5 in the cytoplasm (rather than on the cell surface) is sufficient...

Journal: :International archives of allergy and immunology 2007
F Rogerieux D Godfrin H Sénéchal A C Motta M Marlière G Peltre G Lacroix

BACKGROUND Air pollution is frequently proposed as a potential cause of the increased incidence of allergy in industrialised countries. Our objective was to investigate the impact of the major gaseous air pollutants on grass pollen allergens. METHODS Timothy grass pollen was exposed to ozone (O(3)), nitrogen dioxide (NO(2)) and sulphur dioxide (SO(2)) alone or in combination. Allergen content...

Journal: :The Biochemical journal 1996
L I Ashmarina M F Robert M A Elsliger G A Mitchell

We previously showed that human liver hydroxymethylglutaryl-CoA (HMG-CoA) lyase (HL; EC 4.1.3.4) is found in both mitochondria and peroxisomes. HL contains a 27-residue N-terminal mitochondrial targeting sequence which in cleaved on mitochondrial entry, as well as a C-terminal Cys-Lys-Leu peroxisomal targeting motif. Because peroxisomal HL has a greater molecular mass and more basic pI value th...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه بوعلی سینا - دانشکده علوم کشاورزی 1392

پایه ها نقش مهمی در افزایش تولید و بهره وری باغات میوه عمل می نمایند. با توجه به افزایش رشد رویشی زیاد و هزینه بالای عملیات داشت و برداشت پایه های بذری گیلاس در سطح تجاری در کشور، نیاز به تولید و تکثیر پایه های با رشد رویشی کم و عملکرد بالا امری ضرورب در باغداری گیلاس به حساب می آید. در این راستا، پایه phl-c که داردی رشد رویشی بسیار کم (ارتفاع درخت درخت از 1 تا 3/5 متر)و عملکرد بالای آن اهمیت ب...

2014
Elisabeth Gadermaier Louise K James Mohamed H Shamji Katrina Blatt Tetiana Garmatiuk Rebecca Beavil Sabine Flicker Peter Valent Stephen R Durham Hannah J Gould Rudolf Valenta

Methods and results Sequence comparison showed a comparable sequence identity of approximately 70% between the 2EF-hand pollen allergens (Timothy grass: Phl p 7; Alder: Aln g 4; Birch: Bet v 4; Turnip rape: Bra r 1; Lamb ́s quarter: Che a 3; Olive: Ole e 3) and a lower sequence identity of 44% with the 4EF-hand allergen from olive pollen (Ole e 8). While patients ́ IgE showed extensive cross-reac...

2015
KAI JING ZHANG SAI CHEN JIAN LIN CHEN LI HUA DONG

Primary hepatic lymphoma (PHL) is an uncommon lymphoid tumor with varied clinical features and treatment outcome. In the present study, the case of a 56-year-old patient with PHL and no clinical presentation was reported. During a routine physical examination, multiple hypodense nodules were incidentally detected in right lobes of the liver and hepatic portal in an abdominal computed tomography...

Journal: :American journal of respiratory and critical care medicine 1998
A Bufe K Gehlhar G Schramm M Schlaak W M Becker

Phl p5 is a major allergen of timothy grass and causes rhinitis and bronchial asthma in nearly all patients allergic to grass pollen. The biochemical processing of this molecule by the nasal mucosa at its first encounter and possible changes of its biologic activity are unknown. Two isoforms of the allergen were expressed in Escherichia coli and subsequently purified. Conversion of these prepar...

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