نتایج جستجو برای: PEI

تعداد نتایج: 2797  

Journal: :iranian journal of pharmaceutical research 0
jung-taek kwon laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. hu-lin jiang 1- laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. 2- school of pharmacy, china pharmaceutical university, nanjing 210009, china. arash minai-tehrani laboratory of toxicology, college of veterinary medicine, seoul 151-742, korea. chang gyu woo nanotechnology and thermal processing laboratory, school of mechanical and aerospace engineering, seoul 151-742, korea. mansoo choi nanotechnology and thermal processing laboratory, school of mechanical and aerospace engineering, seoul 151-742, korea. chong-su cho research institute for agriculture and life sciences, seoul national university, seoul 151-742, korea.

chitosan-graft-polyethylenimine (chi-g-pei) copolymer has been used for theimprovement of low transfection efficiency of chitosan. the present study aims to test thepulmonary toxicity and efficiency of chi-g-pei as an aerosol gene carrier. mice were exposedto aerosol containing green-fluorescent protein (gfp)-polyethylenimine (pei) or gfp-chig-pei complexes for 30 min during the development of ...

Integrally-skinned asymmetric Polyetherimide/Poly (vinyl alcohol) (PEI/PVA) hollow fber membranes for pervaporation dehydration were fabricated by non-solvent induced phase inversion. PVA inside the PEI matrix could be crosslinked to provide membrane performance stability during long term operation. The effects of different PEI/PVA blend ratio, external coagulant type and...

Chitosan-graft-polyethylenimine (CHI-g-PEI) copolymer has been used for theimprovement of low transfection efficiency of chitosan. The present study aims to test thepulmonary toxicity and efficiency of CHI-g-PEI as an aerosol gene carrier. Mice were exposedto aerosol containing green-fluorescent protein (GFP)-polyethylenimine (PEI) or GFP-CHIg-PEI complexes for 30 min during the development of ...

Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties. However, the low efficiency of the gene delivery by these copolymers is an obstacle to gene therapy. Here, we have investigated nanoparticles formulated using the p...

Tri-block poly (lactide) poly(ethylene glycol) poly(lactide) (PLA–PEG–PLA) copolymers are among the most attractive nano-carriers for gene delivery into mammalian cells, due to their biocompatibility and biodegradability properties. However, the low efficiency of the gene delivery by these copolymers is an obstacle to gene therapy. Here, we have investigated nanoparticles formulated using the p...

Abstract Purpose: our goal is to reduce the release rate of methotrexate (MTX) and increase cell death efficiency. Methods: Carboxylated multi-walled carbon nanotubes (MWCNT-COOH) were functionalized with MTX as a cytotoxic agent, FA as a targeting moiety and polyethylene amine (PEI) as a hydrophilic agent. Ultimately, MWCNT-MTX and MWCNT-MTX-PEI-FA were synthesized. Methotrexate re...

Abstract Purpose: our goal is to reduce the release rate of methotrexate (MTX) and increase cell death efficiency. Methods: Carboxylated multi-walled carbon nanotubes (MWCNT-COOH) were functionalized with MTX as a cytotoxic agent, FA as a targeting moiety and polyethylene amine (PEI) as a hydrophilic agent. Ultimately, MWCNT-MTX and MWCNT-MTX-PEI-FA were synthesized. Methotrexate re...

Journal: :iranian journal of basic medical sciences 0
reza k. oskuee department of biotechnology, pharmaceutical and biotechnology research centers, school of pharmacy, mashhad university of medical sciences, mashhad, iran ali dehshahri department of biotechnology, pharmaceutical and biotechnology research centers, school of pharmacy, mashhad university of medical sciences, mashhad, iran wayne. t. shier department of medicinal chemistry, university of minnesota-twin cities, minneapolis, mn 55455, usa mohammad ramezani department of biotechnology, pharmaceutical and biotechnology research centers, school of pharmacy, mashhad university of medical sciences, mashhad, iran

objective polyethylenimine (pei), a readily available synthetic polycation which has high transfection efficiency owing to its buffering capacity was introduced for transfection a few years ago. but it has been reported that pei is cytotoxic in many cell lines. in this study, in order to enhance the transfection efficiency of 10 kda pei and reduce its toxicity, hydrophobic residues were grafted...

Journal: :journal of paramedical sciences 0
elham malakooty poor department of stem cells and developmental biology at cell sciences research center, royan institute for stem cell biology and technology, acecr, tehran mohamadreza baghaban eslaminejad department of stem cells and developmental biology at cell sciences research center, royan institute for stem cell biology and technology, acecr, tehran fatemeh bagheri department of stem cells and developmental biology at cell sciences research center, royan institute for stem cell biology and technology, acecr, tehran esmail mollarazi department of nuclear pharmacy, faculty of pharmacy, tehran university of medical sciences,tehran nematollah gheibi cellular and molecular research center,qazvin university of medical sciences, qazvin

this study discusses the effect of complexes of chitosan grafted polyethylenimine(ch-pei) with plasmid dna on viability of mesenchymal stem cells(mscs) derived from human marrow. ch-pei/pdna nanoparticles were synthesized through the complex coacervation method using pires plasmid containing green fluorescent protein (gfp) gene. to confirm the complexation, samples were run through an agarose g...

2012
Weiwei Tong Xueyan Cao Shihui Wen Rui Guo Mingwu Shen Jianhua Wang Xiangyang Shi

There is a general necessity to improve the specificity and efficiency of the polymerase chain reaction (PCR), and exploring the PCR-enhancing mechanism still remains a great challenge. In this paper we report the use of branched polyethyleneimine (PEI)-based derivatives and hybrid nanocomposites as a novel class of enhancers to improve the specificity and efficiency of a nonspecific PCR system...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید