نتایج جستجو برای: PD-1

تعداد نتایج: 2788461  

Journal: :iranian journal of allergy, asthma and immunology 0
mohammad reza javan department of immunology, faculty of medicine, zabol university of medical sciences, zabol, iran and department of immunology, school of medicine, tabriz university of medical sciences, tabriz, iran saeed aslani department of immunology, school of medicine, tehran university of medical sciences, tehran, iran mohammad reza zamani department of immunology, school of medicine, tehran university of medical sciences, tehran, iran and network of immunity in infection, autoimmunity and malignancy (niima), universal scientific education and research network (usern), tehran, iran javad rostamnejad department of genetics, school of medicine, shahid beheshti university of medical sciences, tehran, iran milad asadi immunology research center, tabriz university of medical sciences, tabriz, iran mahdi farhoodi department of neurology, neurosciences research center, tabriz university of medical sciences, tabriz, iran

programmed cell death-1 (pd-1) and its ligands, pd-l1 and pd-l2, have been regarded as important immune system regulatory molecules. the aberrant expression of the molecules has been related to several autoimmune disorders. this study is aimed to assess the mrna expression level of pd-1, pd-l1, and pd-l2 molecules in the peripheral blood mononuclear mells (pbmcs) from multiple sclerosis (ms) pa...

Journal: :Current Opinion in Pharmacology 2015

2017
Jie Bai Zhitao Gao Xiang Li Liang Dong Weidong Han Jing Nie

Immune checkpoint blockades, such as inhibitors against programmed death 1 (PD-1) and its ligand (PD-L1), have received extensive attention in the past decade because of their dramatic clinical outcomes in advanced malignancies. However, both primary and acquired resistance becomes one of the major obstacles, which greatly limits the long-lasting effects and wide application of PD-1/PD-L1 block...

Journal: :Cell 2015

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