ovine pulmonary adenocarcinoma (opa) was studied in the lungs of 15 naturally-affected sheep (9 with classical and 6 atypical lesions) by transmission electron microscopy. two lung samples from normal sheep were used to develop the ultrastructural criteria. pathologic lesions consisted of focal-multifocal to coalescent nodules or masses in the cranioventral or diaphragmatic lobes. ultrastructur...

ovine pulmonary adenocarcinoma (opa) is a contagious and transmissible lung cancer of sheepresembling human bronchiolo-alveolar carcinoma. in the present study, lungs of 9400 sheep slaughtered infars province, iran were examined morphopathologically. the opa was diagnosed in the lungs of 21(0.22%) out of 9400 sheep. frequency of involvement of different lobes in the affected lungs was includeda...

Aneurysm of the pulmonary artery is a rare condition in animals, and to our knowledge it has never been reported association with neoplasia. This report describes case an adult female sheep “Churra Galega Bragançana” breed aneurysm associated lung cancer (ovine adenocarcinoma).

BACKGROUND: Ovine pulmonary adenocarcinoma (OPA) is a worldwide contagious bronchioalveolar carcinoma caused by infection of a beta retrovirus in sheep and less in goat. Neoplastic proliferation of type II pneumocytes and clara cells, produce papillary to acinar tumoral pattern with infiltration of macrophages, lymphocytes and plasma cells and interstitial fibrosis tissue. OBJECTIVES: This stud...

sheep (ovine) pulmonary adenocarcinoma (spa), also known as ovine pulmonary adneomatosis (opa),jaagsiekte and ovine pulmonary carcinoma (opc) is a contagious lung tumor in sheep and, more rarely, ingoats. this study was carried out in khuzestan, in the southwest of iran for a period of six months. a totalnumber of 3985 native breed goats were clinically inspected and postmortem examination was ...

Sheep (ovine) pulmonary adenocarcinoma (SPA), also known as ovine pulmonary adneomatosis (OPA),jaagsiekte and ovine pulmonary carcinoma (OPC) is a contagious lung tumor in sheep and, more rarely, ingoats. This study was carried out in Khuzestan, in the southwest of Iran for a period of six months. A totalnumber of 3985 native breed goats were clinically inspected and postmortem examination was ...

Ovine pulmonary adenocarcinoma (OPA) was studied in the lungs of 15 naturally-affected sheep (9 with classical and 6 atypical lesions) by transmission electron microscopy. Two lung samples from normal sheep were used to develop the ultrastructural criteria. Pathologic lesions consisted of focal-multifocal to coalescent nodules or masses in the cranioventral or diaphragmatic lobes. Ultrastructur...

Valvular endocarditis was diagnosed during a routine flock screen for ovine pulmonary adenocarcinoma (OPA) in 10-month-old ewe lamb with 2-month history of weight loss. Ultrasound examination demonstrated right caudoventral pleuritis presenting as hyperechoic thickening the pleura and irregular lesions measuring approximately 12–15 mm, replacing normal tricuspid mitral valves. The sheep euthana...

Ovine pulmonary adenocarcinoma (OPA) is a lung cancer strikingly similar to the pneumonic-type mixed invasive adenocarcinoma with a predominant bronchioloalveolar component in humans. Telomerase activity in OPA and the potential involvement of the kinase Akt in telomerase activation and regulation of cell proliferation were investigated. Lung tissues were collected from sheep with a histopathol...