CONTEXT Frozen section (FS) evaluation of central nervous system (CNS) lesions provides an assessment of specimen adequacy and facilitates triage for ancillary studies. Frozen section also provides an accurate preliminary diagnosis; however, certain lesions are recognized to cause diagnostic challenges at FS. OBJECTIVE To identify cases in which there was a discrepancy between the FS diagnosi...

background: presence of discordance between the gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. in this study, we determined the accuracy of gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the degree of overgrading and undergrading of prostatic adenocarcinoma in our center, which is one...

Long after worldwide acceptance of the GIA-established standard of UV-free, daylight-colour-balanced illumination for the correct colour grading of a diamond's “true body colour”, an examination of diamond trade and laboratory grading practices finds nearly everyone, including GIA, employing some type of fluorescent tube lighting. GIA taught that this lighting “causes fluorescent diamonds to be...

BACKGROUND Presence of discordance between the Gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. In this study, we determined the accuracy of Gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the degree of overgrading and undergrading of prostatic adenocarcinoma in our center, which is one ...

Staging and grading of bladder cancer have a substantial impact on patients' prognosis. However, due to the relatively low quality and quantity of specimens from transurethral resection (TUR), initial histopathological examination may not be fully reliable. The aim of this study was to assess the repeatability of staging and grading in post-TUR and post-radical cystectomy (RC) specimens. Stagin...

PURPOSE Single positive core in a prostate biopsy is usually associated with indolent prostate cancer (PCa) and is one of the active surveillance (AS) inclusion criteria. We investigated whether single positive core PCa at biopsy could define an archetype of low-risk disease. MATERIALS AND METHODS A total of 1320 consecutive patients were enrolled. Among them, 249 patients with single positiv...

AIM To evaluate the severity of airway obstruction in patients affected by chronic obstructive pulmonary disease (COPD) in the presence of concomitant restriction due to morbid obesity. METHODS Lung function test, six-minute walking distance (6MWD) test, body mass index measurement (BMI), and determination of dyspnoea using the Modified Medical Research Council Dyspnoea Scale (MMRC) were perf...

BACKGROUND Discordance between the Gleason scores of prostate needle biopsies and radical prostatectomy specimens has been reported by several investigators. We conducted this study to determine if increasing the number of prostate needle biopsies in patients with prostate cancer improves the accuracy of Gleason scores in the Taiwanese population. METHODS Between March 2000 and September 2009...

Background: Presence of discordance between the Gleason score on needle biopsy and the score of radical prostatectomy specimen is common and universal. In this study, we determined the accuracy of Gleason grading of biopsies in predicting histological grading of radical prostatectomy specimens and the degree of overgrading and undergrading of prostatic adenocarcinoma i...