نتایج جستجو برای: Ovarian Stem Cells

تعداد نتایج: 1568347  

Journal: :international journal of hematology-oncology and stem cell research 0
abdolreza ardeshiry lajimi stem cell biology department, stem cell technology research center, tehran, iran. majid farshdousti hagh division of laboratory hematology and blood banking, faculty of medicine, tabriz university of medical sciences, tabriz, iran. najmaldin saki research center of thalassemia & hemoglobinopathy, ahvaz jundishapur university of medical sciences, ahvaz, iran. esmaeil mortaz division of pharmacology and pathophysiology, utrecht institute for pharmaceutical sciences, faculty of sciences, utrecht university, utrecht, the netherlands. masoud soleimani hematology department, faculty of medical science, tarbiat modares university, tehran, iran. fakher rahim toxicology research center, ahvaz jundishapur, university of medical sciences, ahvaz, iran.

multiple sclerosis is an inflammatory disease of the central nervous system in which t cells experience a second phase of activation, which ultimately leads to axonal demyelination and neurological disability. the recent advances in stem cell therapies may serve as potential treatments for neurological disorders. there are broad types of stem cells such as neural, embryonic, mesenchymal and hem...

Abdolmaleki, Arash, Dezfoulian, Mahrouz, Ghoreishi, Seyed Amin, maleki, masoud,

Background & Aims: Stem cells are undifferentiated cells and are found in different tissues. These cells have capacity of self-renewal and differentiation into other lineages. Granulosa cells (GCs) are the multipotent stem cells. In the present research we evaluated the differentiation potential of GCs into keratinocytes. Material & Methods: GCs were cultured after enzymatic isolation from ova...

2015
Youssef A. Rezk Kun Yang Shoumei Bai Karen Mclean Carolyn Johnston R. Kevin Reynolds Ronald J. Buckanovich

Objective: Aldehyde dehydrogenase (ALDH) enzymatic activity identifies ovarian cancer stem-like cells. We investigated the antineoplastic activity of the ALDH inhibitor Disulfiram on bulk ovarian cancer cells and CD133+/ALDH+ cancer stem-like cells. Study Design: Ovarian cancer cell lines, human ovarian surface epithelial cells, and mesenchymal stem cells were treated with increasing concentrat...

Journal: :journal of chemical health risks 0
narges bagherpour school of biology, damghan university, damghan, iran saeed zavareh school of biology, damghan university, damghan, iran institute of biological sciences, damghan university, damghan, iran mohamad taghi ghorbanian school of biology, damghan university, damghan, iran institute of biological sciences, damghan university, damghan, iran

the transcriptional factor sox2 regulates the expression of some of the developmental genes, which are essential for the maintenance of pluripotency of stem cells. sox2 also expresses in the female gamete during folliculogenesis, but its role remains ambiguous. the aim of this study was to investigate the expression of sox2 in the mice ovarian tissue during different stage of estrous cycle. adu...

2016
Haifeng Ye Xiaoyan Li Tuochen Zheng Xia Liang Jia Li Jian Huang Zezheng Pan Yuehui Zheng

In addition to its role in maintaining organism homeostasis, the immune system also plays a crucial role in the modulation of ovarian function, as it regulates ovarian development, follicular maturation, ovulation and the formation of the corpus luteum. Ovarian germline stem cells are pluripotent stem cells derived from the ovarian cortex that can differentiate into ovarian germ cells and prima...

2011
Karina Dahl Steffensen Ayesha B. Alvero Yang Yang Marianne Waldstrøm Pei Hui Jennie C. Holmberg Dan-Arin Silasi Anders Jakobsen Thomas Rutherford Gil Mor

Epithelial ovarian cancer stem cells (EOC stem cells) have been associated with recurrence and chemoresistance. CD44 and CK18 are highly expressed in cancer stem cells and function as tools for their identification and characterization. We investigated the association between the number of CD44+ EOC stem cells in ovarian cancer tumors and progression-free survival. EOC stem cells exist as clust...

Journal: :international journal of reproductive biomedicine 0
karim nayernia jae ho lee wolfgang engel jessica nolte nadja drusenheimer kristina rathsack

germline and somatic stem cells are distinct types of stem cells that are dedicated to reproduction and somatic tissue regeneration, respectively. germline stem cells (gscs), which can self-renew and generate gametes, are unique stem cells in that they are solely dedicated to transmit genetic information from generation to generation. we developed a strategy for the establishment of germline st...

Journal: :archives of trauma research 0
serkan akpancar department of orthopedic surgery, gulhane military hospital, ankara, turkey; department of orthopedic surgery, gulhane military medicine academy, ankara, turkey. tel: +90-5443229700, fax: +90-3124045500 oner tatar department of orthopedic surgery, air force academy kasımpaşa military hospital, istanbul, turkey hasan turgut department of orthopedic surgery, bursa military hospital, bursa, turkey faruk akyildiz department of orthopedic surgery, gulhane military hospital, ankara, turkey safak ekinci department of orthopedic surgery, agri military hospital, agri, turkey

conclusions large amounts of preclinical studies have been made of stem cells and there is an increasing interest to perform these studies within the human population but preclinical studies are insufficient; therefore, much more and efficient studies should be conducted to evaluate the efficacy and safety of stem cells. context musculoskeletal injuries may be painful, troublesome, life limitin...

Journal: :International journal of molecular medicine 2014
Yi-Fei Chen Shu-Ying Wang Hong Shen Xiao-Fen Yao Feng-Li Zhang Dongmei Lai

The difficulties faced in the effective treatment of ovarian cancer are multifactorial, but are mainly associated with relapse and drug resistance. Cancer stem-like cells have been reported to be an important contributor to these hindering factors. In this study, we aimed to investigate the anticancer activities of a bioactive fungal metabolite, namely terrein, against the human epithelial ovar...

Journal: :European review for medical and pharmacological sciences 2014
H C Yan L S Fang J Xu Y Y Qiu X M Lin H X Huang Q Y Han

OBJECTIVE Identifying the biological characteristics of previously screened ovarian cancer cell line HO8910-derived stem cells. MATERIALS AND METHODS The pre-screening of ovarian cancer cell line HO8910-derived stem cells were subcultured (HO8910 cells were used as a control group) in serum-free medium. Firstly, the capacities of forming spheroids and self-renewal were observed. Then ovarian ...

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