Clear cell carcinoma of ovary is uncommon ovarian tumour that arises from surface epithelium of ovary. It has well-known association with ovarian endometriosis. We report here the first case of bilateral clear cell carcinoma of ovaries in a 40-year-old woman with a 17-year history of bilateral ovarian endometriosis. In addition, during the longstanding duration of the endometriosis, the patient...

results totally, 101women were evaluated during the study. endometriosis was present at laparoscopy in 58 patients. mean age and the duration of infertility were calculated 30.78 ± 4.79 and 4.2 ± 2.91 years respectively. frequencies of each sonographic finding were as follow: echogenic points (%31.68), ovarian endometrioma (%30.69), blurred ovary margin (%7.92), fixation of ovaries (%15.9), dev...

Infertility is a main manifestation of endometriosis, though the exact pathogenesis endometriosis-associated infertility remains unclear. Compromised ovarian functions may be one causes endometriosis related infertility. The function can classified into three basic elements, (1) production hormones, (2) maintenance follicular development until ovulation, and (3) reservoir dormant oocytes (ovari...

Background We intended to determine the incidence of endometriosis at diagnostic laparoscopy for infertility problem and pelvic pain and/or cyst. In addition we aimed to evaluate symptoms, different stages and locations of endometriosis in fertile or infertile endometriosis patients. MaterialsAndMethods This observational cross-sectional study was performed in the Department of Obstetrics and G...

Inflammatory cells play important roles in progression of solid neoplasms including ovarian cancers. Tumor-associated macrophages (TAMs) contribute to angiogenesis and immune suppression by modulating microenvironment. Ovarian cancer develops occasionally on the bases of endometriosis, a chronic inflammatory disease. We have recently demonstrated differential expressions of CXCR3 variants in en...

Endometriosis is one of the most frequently encountered benign diseases in gynecology. Complete resolution of endometriosis is not yet possible, but therapy has essentially three main objectives: (1) to preserve and improve fertility, (2) to reduce pain, and (3) to delay recurrence for as long as possible. The aim of this paper is to focus on fertility preservation in women with severe endometr...

STUDY QUESTION Is ovarian or extra-ovarian endometriosis associated with an increased risk of ovarian cancer and borderline ovarian tumours (BOT)? SUMMARY ANSWER We found a 3- to 8-fold increased risk of ovarian tumours associated with endometriosis: the magnitude of the risk increase depended on the definition of endometriosis. WHAT IS KNOWN ALREADY There is increasing evidence of an assoc...

BACKGROUND Despite enormous efforts to dissect the role of endometriosis in ovarian cancer development, the difference in prognosis between ovarian cancer patients with or without endometriosis remains elusive. The purpose of this study is to assess the association between endometriosis and the prognosis in patients with ovarian cancer. RESULTS Ovarian cancer arising in endometriosis tended t...

Clear cell carcinoma of ovary is uncommon ovarian tumour that arises from surface epithelium of ovary. It has well-known association with ovarian endometriosis. We report here the first case of bilateral clear cell carcinoma of ovaries in a 40-year-old woman with a 17-year history of bilateral ovarian endometriosis. In addition, during the longstanding duration of the endometriosis, the patient...

There is still not enough evidence that endometriosis per se and infertility are causally related. While extensive pelvic adhesions or the loss of ovarian tissue clearly bears out the causative role of endometriosis this is more difficult in other patients. Several randomized controlled trials and observational studies have in fact reported almost uniform negative results: • spontaneous pregnan...