background: breast cancer is the most common malignancy in women. breast cancer type 1 susceptibility gene (brca1) is a tumor suppressor gene, involved in dna damage repair and in 81% of the breast-ovarian cancer families were due to brca1. in some clinically investigated genes, the intragenic marker polymorphism is important and the screening of such mutations is faster by using short tandem r...

female cancer, especially breast and gynecologic cancers are considered multistage disease, highly influenced by risk and protective factors and/or screening preventive modalities. consequences of all these factors result in the trend of change over time.in this comparative study, based on data of national cancer registry of iran 2004 published by iranian ministry of health, age - standard inci...

background: ovarian cancer is the most fatal tumor of female's reproductive system, and several genetics and environmental factors are involved in its development. various studies have already identified suitable biomarkers to facilitate the early detection, prognosis evaluation, and the assessment of treatment response. however, the aim of this review was to investigate the role of long n...

background: the best management for an ovarian mass is provided by appropriate prediction of malignancy. the aim of our study is to construct and validate a new malignancy probability score based on four simple sonographic findings and age. methods: in a cross sectional study; histopathological files of 3303 ovarian mass patients and tertiary hospitals, have reviewed within 6 years (2000-2006)....

background: ovarian cancer is the fifth leading cause of death from malignancy in women. cd4 +cd25+foxp3+ regulatory t (treg) cells are a subset of t lymphocytes with great inhibitory impact on immune response. objectives: to investigate the percentage of cd4 +cd25+foxp3+ regulatory t cells in the peripheral blood of the iranian patients with epithelial ovarian cancer compared to healthy women ...

tuberculosis (tb) is the most common infectious cause of human death. after the lung, genitourinary tract is the most common site for tb infection. pelvic tuberculosis should be considered in young women presented with pelvic mass, ascites, fever, an elevated ca125 level, negative cytology, and positive history of contact with affected person. a 24- year- old girl presented as stage iv ovarian ...

ovarian cancer is the most lethal gynecological cancer and about 70% of the patients are advanced stagein the time of diagnosis. decision about management (surgical debulking versus neoadjuant chemotherapy) in ovarian cancer patients is dependent on initial staging by abdominopelvic mdct or mri, so, radiologist expertise on ovarian cancer staging is very important. involvement of mesenteric roo...

background: inhibin is a dimeric glycoprotein that has a depressive effect on the anterior hypophyse secretion. the level of this tumor marker is undetectable in menopause women. in patients with gynecological cancer, especially granulosa and epidermal-type (mucinous), ovarian cancers considerable increase in the serum level of inhibin has been reported. the increased level of inhibin has been ...

background and aims: ovarian cancer is one of most common causes of cancer related women's mortalities. human papilloma virus is a known factor concerning cervical cancer but its role in causing ovarian cancer is not yet verified. a few studies also identified hpv dna in ovarian carcinoma tissues. however, some studies did not detect hpv dna in ovarian carcinoma tissues. in this article, we inv...

background: chlamydia trachomatis (c. trachomatis) and mycoplasma genitalium (m. genitalium) are considered factors in cervical and ovarian cancer and are associated with flaky cell carcinoma of the cervix. the role of steady infection, leading to chronic inflammation, in the of ovarian cancer has received very little consideration, although a background of pelvic inflammatory disease (pid) is ...