we aimed to study the mntnhex-2-pyp effect on some markers of lung antioxidant defence system in mice asthma model.the study was carried out on 28 c57b1/6 mice divided into four treatment groups: group 1 - controls; group 2 - injected and inhaled with ovalbumin; group 3 - treated with mntnhex-2-pyp and inhaled with phosphate buffered saline; group 4 - injected with ovalbumin and mntnhex-2-pyp b...

Objective(s): P2X4R is expressed in immunocyte and lung tissues. It has been a focus in inflammatory responses recently. This study investigated whether blockage of P2X4R attenuates allergic inflammation by modulating T cell response in ovalbumin-sensitized mice. Materials and Methods: Ovalbumin was used to sensitize and challenge for a mouse model. Intranasal application of 5-BDBD, P2X4R antag...

BackgroundOral immunotherapy (OIT) aims to establish desensitization and sustained unresponsiveness (SU) in patients with food allergy by ingestion of gradually increasing doses specific allergens. However, little is known about the mechanisms which OIT induces SU allergens.ObjectivesWe investigated role Notch signaling, controls cell fate decisions many types immune cells induction treatment.M...

This investigation was designed to determine the effect of intact ovalbumin and mannose-conjugatedovalbumin on the prevention of Salmonella typhimurium adherence to the epithelium of small intestine ofchickens. Mannose-conjugated ovalbumin was produced by Maillard-type reaction between chickenovalbumin and D-mannose at 60°C. The results revealed that incubation up to 96 hrs caused the highestam...

Tryptophan was isolated from rat feces as an active compound against ovalbumin permeation in an in vitro Caco-2 cell model. Tryptophan dose-dependently inhibited ovalbumin permeation with accompanying increase in transepithelial electric resistance, and its inhibitory activity reached a plateau at 10 mM. Brown Norway rats were sensitized by intragastric administration of ovalbumin together with...

objective(s):bone marrow-derived mesenchymal stem cells (bmscs) have attracted significant interest to treat asthma and its complication. in this study, the effects of bmscs on lung pathology and inflammation in an ovalbumin-induced asthma model in mouse were examined. materials and methods:balb/c mice were divided into three groups: control group (animals were not sensitized), asthma group (an...

this investigation was designed to determine the effect of intact ovalbumin and mannose-conjugatedovalbumin on the prevention of salmonella typhimurium adherence to the epithelium of small intestine ofchickens. mannose-conjugated ovalbumin was produced by maillard-type reaction between chickenovalbumin and d-mannose at 60°c. the results revealed that incubation up to 96 hrs caused the highestam...