Birth defects belong to the most serious side effects of pharmaceutical compounds or environmental chemicals. In vivo, teratogens most often affect the normal development of bones, causing growth retardation, limb defects or craniofacial malformations. The embryonic stem cell test (EST) is one of the most promising models that allow the in vitro prediction of embryotoxicity, with one of its end...

silver nanoparticles (ag nps) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. present study compares the tissue levels of ag nps in different organs of guiana pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the ag nps tissue levels. before toxicological assessments,the ...

Cadmium (Cd); a non-essential trace element; is one of the most toxic heavy metals in the environment for plants and animals [1]. Environmental contamination by Cd results from its industrial use and its presence in agricultural fertilizers. This is a subject of serious concern since the metal is known to enter the food chain and can undergo bioaccumulation; endangering human health [2]. In hum...

Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...

Silver nanoparticles (Ag NPs) have been widely used as new potent antimicrobial agents in cosmetic and hygienic products. Present study compares the tissue levels of Ag NPs in different organs of Guiana Pigs quantitatively after dermal application and analysis the morphological changes and pathological abnormalities on the basis of the Ag NPs tissue levels. Before toxicological assessments,the...