Osteosarcoma is the most frequent malignant bone tumor with a peak incidence in the second and third decades of life. Diagnosis of patients with osteosarcoma is limited to clinico-pathological parameters whereas molecular markers of tumor initiation and promotion have not yet been identified. We aimed to study the expression of the anti-apoptotic survivin gene in osteosarcoma specimens. A total...

abstract   background: parosteal osteosarcoma is rare low-grade malignancy which arises on the surface of the metaphysis of long bones it has a low propensity to metastasize. different surgical treatment options including marginal resection, wide resection and amputation were recommended for the tumor. the purpose of the study was to assess the results of different surgical treatment of the les...

     Osteosarcoma (OS) is a malignant tumor that induces formation of osteoid or immature bone and rarely occurs in maxilla. Maxillofacial OSs are reported to occur in the third to fifth decades that is 1-2 decades later than the mean age for OS of long bones. The present case is a 62-year-old man with facial asymmetry and pain in his left upper jaw. Intraoral examination showed a bony hard, te...

osteosarcoma is a primary malignant tumor of bone, which can involve jaws. this article reviews osteosarcoma of the jaws referred to the department of oral pathology, dental faculty of tehran university of medical sicences and pathology department of cancer institiute in imam khomeini hospital during 30 years from 1349 to 1378 and also reviews jaw osteosarcoma in english literature. the purpose...

Background/Aim: Osteosarcoma is the most frequent malignant bone tumor. Failure of first-line therapy results in poor prognosis osteosarcoma. In present report, we examined efficacy combination oral recombinant methioninase (o-rMETase) and docetaxel (DOC) on an osteosarcoma patient-derived orthotopic xenograft (PDOX) mouse model. Materials Methods: Osteosarcoma-PDOX models were established by t...

objective(s): the present study was designed to investigate the antibacterial function and pharmacological effect of elephant garlic (allium ampeloprasum var. ampeloprasum) on u2os human osteosarcoma cells.   materials and methods: seven kinds of bacteria were reconstituted, inoculated and tested in this research to evaluate elephant garlic antibacterial activity. by the means of facs analysis,...

Osteosarcoma is a common primary malignant bone tumor in young adults presenting with back and chest pain complaints. Here, we presented rare case of osteosarcoma.

  Objective(s): The present study was designed to investigate the antibacterial function and pharmacological effect of elephant garlic (Allium ampeloprasum var. ampeloprasum) on U2OS human osteosarcoma cells.   Materials and Methods: Seven kinds of bacteria were reconstituted, inoculated and tested in this research to evaluate elephant garlic antibacterial activity. By the means ...

Osteosarcoma, the most common bone cancer, leads to a poor survival rate of patients. Drug targeting employing hydroxyapatite (HAp)-based nanocarriers represents fascinating choice for non-invasive treatment osteosarcoma.

Osteosarcoma of the foot is exceedingly uncommon, and as a result, very little known about patient tumor characteristics. In addition, prognosis may be grim due to delayed presentation misdiagnosis. A diagnosis osteosarcoma, regardless location, not only reduce long-term survival but also modify treatment plan, resulting in less favorable functional cosmetic outcomes. Here we report diagnostic ...