previous studies on etiology of squamous cell carcinoma (scc) of the tongue have reported results with respect to long term exposure to cigarette smoking and alcohol abuse. the aim of this study was to investigate risk factors for scc of the tongue in a set of patients with minimum exposure to cigarette smoking and alcohol. sixty four cases with diagnosis of oral tongue scc were reviewed in thi...

Introduction: Metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. The most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. Renal cell carcinoma accounts for nearly 3% of all adult malignancies. It usually metastasizes to the lungs,...

BACKGROUND Resistance to anticancer agents is a major obstacle for successful chemotherapy in tongue squamous cancer. Sam68 is an oncogenic-related protein in oral tongue squamous cell carcinoma functions as a signaling molecule mediating apoptosis, whose over-expression is associated with the clinicopathologic characteristics and prognosis of patients. The present study was to examine the effe...

introduction: metastatic lesions of the oral cavity are extremely rare, accounting for approximately 1% of all malignant oral tumors. the most common primary sources of metastatic tumors in the oral region are, from the most to the least common, the breast, lung, kidney, bone, and colon. renal cell carcinoma accounts for nearly 3% of all adult malignancies. it usually metastasizes to the lungs,...

background: betel nut and betel quid chewing are from major etiological factor for oral cancer. they also increase the risk of systemic diseases such as asthma, diabetes mellitus, metabolic syndrome, myocardial infarction, hypertension, and other cardiovascular diseases. methods: sixty three patients of oral cancer in our institution during jan. 2007 to may 2011 were included in our study. this...

Apoptosis-related protein B-cell lymphoma-extra large (Bcl-xL) has a crucial role in the control of cell death through its inhibition of apoptosis. This study was designed to investigate the expression of Bcl-xL in relation to the development of tongue carcinoma and whether it has potential as a marker for the clinical diagnosis of tongue carcinoma and as a therapeutic target to evaluate the dy...

Introduction: The clinical outcome of patients with squamous cell carcinoma (SCC) located in the head and neck has remained poor despite ongoing advances in diagnosis and management. Interleukin-6(IL-6) is a multi-functional cytokine that plays an important role in the process of cell differentiation and is increased in several malignancies. The aim of this study was to investigate the serum le...

Carcinoma of the oral tongue is one of the most common sub sites of oral cancer. Comparative worldwide studies have reported its incidence to be much higher in India (Moore et al., 2000; Mishra and Meherotra, 2014). In Chennai, India, oral tongue squamous cell carcinoma (OTSCC) represents 5% and 1.6% of incident cancers of all sites among males and females respectively as per the reports of pop...

Introduction: Regarding the lack of data on the  frequency of oral cancer in Babol, the aim of this study was to evaluate the frequency of oral cancer in Babol during 2012-2016. Material & Methods: This retrospective cross-sectional study was performed using pathology sheet records of oral cancer patients during 2012-2016. Survival status of patients was collected through telephone contact. R...