OPTIMAL ANTI-INFECTIVE DRUG DOSES FOR CHILDREN Anti-infective agents are among the most commonly prescribed drugs in children. What is considered the optimal dose of an anti-infective agent is determined by how the child handles the drug and the resulting drug concentration in the body (pharmacokinetics, PK) as well as by the effect of the drug on the target pathogen (pharmacodynamics, PD). Amo...

abstract objective: the aim of this study was to evaluate the efficacy of antibiotic-loaded bone cement in controlling local infection and in regard to its physical characteristics, elastic modulus, and tensile strength in-vitro. methods: acrylic bone cement, based on polymethylmethacrylate (pmma) was mixed with the powder form of three antibiotics, i.e., gentamicin, tobramycin, and cefuroxime ...

  Abstract   Objective: The aim of this study was to evaluate the efficacy of antibiotic-loaded bone   cement in controlling local infection and in regard to its physical characteristics, elastic   modulus, and tensile strength in-vitro.   Methods: Acrylic bone cement, based on polymethylmethacrylate (PMMA) was   mixed with the powder form of three antibiotics, i.e., gentamicin, tobramycin, and...