نتایج جستجو برای: Ocular Mini-tablet

تعداد نتایج: 119642  

Journal: :iranian journal of pharmaceutical research 0
seyed alireza mortazavi department of pharmaceutics, school of pharmacy, shahid beheshti university of medical sciences, tehran, iran. yasaman ghadjahani pharmaceutical sciences branch islamic azad university, tehran, iran hoda mahmoodi pharmaceutical sciences branch islamic azad university, tehran, iran farzaneh mehtarpour pharmaceutical sciences branch islamic azad university, tehran, iran zahra jaffariazar pharmaceutical sciences branch islamic azad university, tehran, iran

the purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of glaucoma. following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. the polymers investigated in this study included cellulose derivatives (hec, cmc, ec) and carbopol971p. mann...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of Glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol971P. Mann...

2014
Seyed Alireza Mortazavi Zahra Jafariazar Yasaman Ghadjahani Hoda Mahmoodi Farzaneh Mehtarpour

The purpose of this study was preparation and evaluation of sustained release matrix type ocular mini-tablets of timolol maleate, as a potential formulation for the treatment of glaucoma. Following the initial studies on timolol maleate powder, it was formulated into ocular mini-tablets. The polymers investigated in this study included cellulose derivatives (HEC, CMC, EC) and Carbopol 971P. Man...

Journal: :Journal of pharmaceutical sciences 2014
Hesham M Tawfeek Imran Y Saleem Matthew Roberts

The aim was to enhance the dissolution of lornoxicam (LOR) and to produce mini-tablets with an optimised system to provide a rapid-release multi-particulate formulation. LOR systems were prepared through co-evaporation with either polyethylene glycol 6000 or Pluronic(®) F-68 (PLU) and adsorption onto Neusilin(®) US2 alone or co-adsorption in the presence of different amounts of polysorbate 80. ...

Journal: :Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society 2015
Antoine Al-Achi Binit Patel

The use of potassium iodide (KI) as a protective agent against accidental radioactive exposure is well established. In this study, we aimed to prepare a KI tablet formulation using a direct compression method. We utilized Design of Experiment (DoE)/mixture design to define the best formulation with predetermined physical qualities as to its dissolution, hardness, assay, disintegration, and angl...

Journal: :Acta pharmaceutica 2015
Khalid M El-Say Tarek A Ahmed Maged F Abdelbary Bahaa E Ali Bader M Aljaeid Ahmed S Zidan

This study was aimed at developing risperidone oral disintegrating mini-tablets (OD-mini-tablets) as age-appropriate formulations and to assess their suitability for infants and pediatric use. An experimental Box-Behnken design was applied to assure high quality of the OD-mini-tablets and reduce product variability. The design was employed to understand the influence of the critical excipient c...

Journal: :Chemical & pharmaceutical bulletin 2008
Shouhei Aikawa Naomi Fujita Hidetoshi Myojo Takashi Hayashi Tadatsugu Tanino

A newly developed mini-scale high shear granulator was used for scale-up study of wet granulation process from 0.2 to 200 L scales. Under various operation conditions and granulation bowl sizes, powder mixture composed of anhydrous caffeine, D-mannitol, dibasic calcium phosphate, pregelatinized starch and corn starch was granulated by adding water. The granules were tabletted, and disintegratio...

Journal: :Journal of optometry 2014
Jennifer S Harthan

Patients with Graves' ophthalmopathy can be very challenging to manage secondary to the complex nature of their disease presentation. Patients may present with a variety of ocular findings including: lid retraction, periorbital and lid swelling, chemosis, conjunctival hyperemia, proptosis, optic neuropathy, restrictive myopathy, exposure keratopathy and/or keratoconjunctivitis sicca. Mini-scler...

Journal: :European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 2015
A-K Vynckier H Lin J A Zeitler J-F Willart E Bongaers J Voorspoels J P Remon C Vervaet

In this study calendering is used as a downstream technique to shape monolithic co-extruded fixed-dose combination products in a continuous way. Co-extrudates with a metoprolol tartrate-loaded sustained-release core and a hydrochlorothiazide-loaded immediate-release coat were produced and immediately shaped into a monolithic drug delivery system via calendering, using chilled rolls with tablet-...

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