Introduction: Quantitative evaluation is recommended to improve diagnostic ability and serial assessment of dopamine transporter (DAT) density scans. We decided to compare the ordered subsets expectation-maximization (OSEM) with filtered back-projection (FBP), and to investigate the impact of different iteration and cut-off frequencies on SBR values. Methods</stro...

Objective (s): Various iterative reconstruction algorithms in nuclear medicine have been introduced in the last three decades. For each new imaging system, it is wise to select appropriate image reconstruction algorithms and evaluate their performance. In this study, three approaches of image reconstruction were developed for a novel desktop open-gantry SPECT system, PERSPECT, to assess their p...

Filtered back projection (FBP) method and maximum likelihood expection maximization (OSEM) method are currently used for reconstruction of SPECT images in clinical studies. The aim of this work is to compare the image quality using different reconstruction techniques of a SPECT phantom as applied to bone scintigraphy. The resolution and contrast of the hot spheres were observed using a phantom ...

UNLABELLED The high-resolution research tomograph (HRRT) is a dedicated human brain PET scanner. At present, iterative reconstruction methods are preferred for reconstructing HRRT studies. However, these iterative reconstruction algorithms show bias in short-duration frames. New algorithms such as the shifted Poisson ordered-subsets expectation maximization (SP-OSEM) and ordered-subsets weighte...

The aim of this study was to validate in vivo the accuracy of a reconstruction-based partial volume correction (PVC), which takes into account the point spread function of the imaging system. The NEMA NU2 Image Quality phantom and five healthy volunteers (using [(11)C]flumazenil) were scanned on both HR+ and high-resolution research tomograph (HRRT) scanners. HR+ data were reconstructed using n...

OBJECTIVES We observed whether clearer tumor delineation and greater tumor to non-tumor (T/N) count ratios could be obtained using an iterative ordered-subsets expectation maximization (OSEM) algorithm than conventional filtered-back projection algorithm (FBP) in the image reconstruction of thallium-201 (201Tl) lung scintigraphy. METHODS In 29 patients with lung cancer and phantom studies, to...

OBJECTIVE Application of distinct positron emission tomography (PET) scan reconstruction algorithms can lead to statistically significant differences in measuring lesion functional properties. We looked at the influence of two-dimensional filtered back projection (2D FBP), two-dimensional ordered subset expectation maximization (2D OSEM), three-dimensional ordered subset expectation maximizatio...

Purpose I-labelled radioligands are commonly used for single-photon emission computed tomography (SPECT) imaging of the dopaminergic system to study the dopamine transporter binding. The aim of this work was to compare the quantitative capabilities of two different SPECT systems through Monte Carlo (MC) simulation. Methods The SimSET MC code was employed to generate simulated projections of a n...

objective: the aim of this study was to evaluate the influences of reconstruction and attenuation correction on the differences in the radioactivity distributions in 123i brain spect obtained by the hybrid spect/ct device. methods: we used the 3-dimensional (3d) brain phantom, which imitates the precise structure of gray mater, white matter and bone regions. it was filled with 123i solution (20...