BACKGROUND Celiac disease (CD) is a disorder associated with body reaction to gluten. After the gluten intake, an immune reaction against the protein occurs and damages villi of small intestine in celiac patients gradually. OBJECTIVES The OSC, a filtering method for minimization of inter- and intra-spectrometer variations that influence on data acquisition, was applied to biofluid NMR data of...

background celiac disease (cd) is a disorder associated with body reaction to gluten. after the gluten intake, an immune reaction against the protein occurs and damages villi of small intestine in celiac patients gradually. objectives the osc, a filtering method for minimization of inter- and intra-spectrometer variations that influence on data acquisition, was applied to biofluid nmr data of c...

Asthma is prevalent in children and cats, and needs means of noninvasive diagnosis. We sought to distinguish noninvasively the differences in 53 cats before and soon after induction of allergic asthma, using NMR spectra of exhaled breath condensate (EBC). Statistical pattern recognition was improved considerably by preprocessing the spectra with probabilistic quotient normalization and glog tra...

A novel chemometric method, region orthogonal signal correction (ROSC), is proposed and applied to pretreat near-infrared (NIR) spectra of blood glucose measured in vivo. Water is the most serious interference component in such kinds of noninvasive measurements, because it shows very high absorbance in the spectra. In the present study, the spectra of blood glucose in the range of 1212 - 1889 n...

Um novo método espectrofotométrico, simples e sensível, foi descrito para determinação simultânea de urânio e tório. O método é baseado na formação de complexos de urânio e tório com Arsenazo III em pH 3,0. Todos os fatores que afetam a sensibilidade foram otimizados e o intervalo dinâmico linear para determinação de cada analito foi encontrado. A determinação simultânea de urânio e tório em mi...

Methods of multiblock bilinear factorizations have increased in popularity in chemistry and biology as recent increases in the availability of information-rich spectroscopic platforms has made collecting multiple spectroscopic observations per sample a practicable possibility. Of the existing multiblock methods, consensus PCA (CPCA-W) and multiblock PLS (MB-PLS) have been shown to bear desirabl...