Despite its various clinical applications, cyclophosphamide (CP), an alkylating chemotherapeutic agent, has demonstrated numerous side effects, including genetic toxicity. This study investigated the protective action of Origanum vulgare L., a powerful antioxidant plant, on the genotoxicity of CP in the mice blood lymphocytes. The mice were pretreated orally with different doses of (50, 100, 20...

background and objective: the medicinal plant origanum vulgare. subsp. vulgare in the lamiaceae family has been widely used by iranian people for the treatment of respiratory, gastrointestinal and neurologic disorders. the present study was carried out to evaluate possible anxiolytic effects of aqueous extract of o. vulgare leaves and the flowering branches in rats.materials and methods: anxiol...

Background and Objective: The medicinal plant Origanum vulgare. subsp. vulgare in the Lamiaceae family has been widely used by Iranian people for the treatment of respiratory, gastrointestinal and neurologic disorders. The present study was carried out to evaluate possible anxiolytic effects of aqueous extract of O. vulgare leaves and the flowering branches in rats.Materials and Methods: Anxiol...

Background: In current study, chemical composition and antibacterial activity of leaves and flowers essential oils of Origanum vulgare ssp. gracile against four food-borne pathogens including  Escherichia coli, Listeria monocytogenes, Salmonella thyphimurium and Staphylococcus aureus were examined. Methods: The different organs (leaves and flowers) of O. vulgare ssp. gracile were har...

background: in current study, chemical composition and antibacterial activity of leaves and flowers essential oils of origanum vulgare ssp. gracile against four food-borne pathogens including  escherichia coli, listeria monocytogenes, salmonella thyphimurium and staphylococcus aureus were examined. methods: the different organs (leaves and flowers) of o. vulgare ssp. gracile were harvested at f...

The aim of this study was to evaluate concentration-dependent antioxidant and anticancer activities of CA and RA in ethanol extracts of three different Oregano species (Origanum onites L., Origanum vulgare L., and Origanum vulgare ssp. hirtum). The study revealed the highest RA antioxidant activity in O. vulgare ssp. hirtum (9550 ± 95 mmol/g) and the lowest in O. vulgare L. (2605 ± 52 mmol/g) (...

Both Origanum vulgare L. subsp. vulgare and O. vulgare subsp. hirtum (Link) Ietsw. occur in the Rhodopes in different habitats. Collection of O. v. subsp. hirtum is forbidden for trade purposes in Bulgaria by law. The aim of this study is to trace the traditional use and collection of both subspecies in the Rhodopes therefore ethnobotanical survey was carried out. O. vulgare was one of the most...

 Background & Objective:  Toxico-pathological effects of herbal plants have always been a major concern, but little information is provided on the toxico-pathological effects of origanum on the fetus. Due to ethical rules and regulations, no drug experiment on the human fetus is permitted; hence, the chick embryo model is used as an ideal opportunity to study the adverse effects of drugs. This ...

The aim of the present work was to determine the in vitro effect of T. vulgaris and O. vulgare essential oils against E. granulosus protoscoleces and cysts. Essential oils were added to the medium resulting in thymol final concentrations of 10 μg/mL. The essential oils had a time-dependent effect provoking the complete loss of protoscolex viability after 72 days of postincubation. The results w...

The antifungal activities of Origanum vulgare essential oil (EO) and of a biocide based on silver and hydrogen peroxide (Sanosil S003) against seven Aspergillus species isolated from different substrata (stone, brick, silk and paper) of cultural heritage objects in Serbia were evaluated. Microdilution, agar dilution and microatmosphere methods were used to determine minimal fungistatic and mini...