Inflammatory reactions are closely associated with the development and progression of epilepsy. It has been shown that inhibition of pro-inflammatory cytokines, which are released from activated astrocytes and microglia, are considered to be an effective therapeutic approach for the treatment of epileptic disorders. Regarding the anti-inflammatory effects of nutmeg (Myristica fragrans Houtt), t...

Inflammatory reactions are closely associated with the development and progression of epilepsy. It has been shown that inhibition of pro-inflammatory cytokines, which are released from activated astrocytes and microglia, are considered to be an effective therapeutic approach for the treatment of epileptic disorders. Regarding the anti-inflammatory effects of nutmeg (Myristica fragrans Houtt), t...

CONTEXT Nutmeg [Myristica fragrans Houtt. (Myristicaceae)] has a long-standing reputation of psychoactivity. Anecdotal reports of nutmeg use as a cheap marijuana substitute, coupled to previous studies reporting a cannabimimetic-like action, suggest that nutmeg may interact with the endocannabinoid system. OBJECTIVE The study evaluates nutmeg fractions for binding capacity with various CNS re...

BACKGROUND Myristica fragrans Houtt. (nutmeg) has been mentioned in Unani medicine to be of value in the management of male sexual disorders. The present study was undertaken to evaluate the aphrodisiac effect of 50% ethanolic extract of nutmeg along with its likely adverse effects and acute toxicity using various animal models. METHODS The suspension of the extract was administered (100, 250...

BACKGROUND Nutmeg a well-known spice used as a folk medicine in India to treat stomach ailments. Worldwide it is commonly used for food preservation and fragrance. Abundant references were given for nutmeg in ayurveda, unani, and siddha as a single drug or as an important constituent in formulations. OBJECTIVE In the present study, nutmeg aqueous extract (NMAET) was evaluated against isoprote...

Nutmeg ingestion in large amounts can cause toxic symptoms such as hallucinations, tachycardia and anticholinergic effects. We describe a case of a 37-year-old woman who experienced an unintentional autointoxication of nutmeg. It is likely that nutmeg intoxication is underreported. We suggest to specifically think of nutmeg ingestion in case of symptoms as mentioned above.

Nutmeg leaf, lemongrass, and bee nests contain bioactive compounds that have potential as mosquito repellents. The purpose of this study was to learn about the bioactivity a combination extract nutmeg nests, well determine efficient repellent lotion recipe from extract. maceration process used for extraction. Total flavonoid content estimated by comparing it quercetin. absorbance value measured...

Nutmeg (Myristica fragrans Houtt.) is native to Indonesia. One of the nutmeg products that are traded and exported seeds. or what commonly called in great demand because it contains many aromatic compounds form essential oils. This study aims extract determine composition seed oils based on differences coat color. Fresh samples were extracted analyzed using GC-MS. The results showed twelve iden...

Seeds of nutmeg are used as spice, but they are also abused because of psychotropic effects described after ingestion of large doses. It was postulated that these effects could be attributable to metabolic formation of amphetamine derivatives from the main nutmeg ingredients elemicin (EL), myristicin (MY), and safrole (SA). In a case of a suspected nutmeg abuse, neither such amphetamine derivat...

In the paper four approaches of upgrading analog circuits analysis tools (SPICE was used) with optimisation loops are compared. In the first approach the optimisation algorithm is coded in Mathematica, which calls SPICE for every circuit analysis. In the second approach the algorithm is coded in Nutmeg. (Nutmeg is an interpreter designed as a user interface for SPICE, but it has all properties ...