نتایج جستجو برای: Nontypeable Haemophilus influenzae

تعداد نتایج: 9957  

2014
Jeroen D. Langereis Jeffrey N. Weiser

Nontypeable Haemophilus influenzae is a frequent cause of noninvasive mucosal inflammatory diseases but may also cause invasive diseases, such as sepsis and meningitis, especially in children and the elderly. Infection by nontypeable Haemophilus influenzae is characterized by recruitment of neutrophilic granulocytes. Despite the presence of a large number of neutrophils, infections with nontype...

Journal: :avicenna journal of medical biotechnology 0

background: nontypeable haemophilus influenzae (nthi) is a common cause of respiratory tract disease and initiates infection by colonization in nasopharynx. the haemophilus influenzae (h. influenzae) hap adhesin is an auto transporter protein that promotes initial interaction with human epithelial cells. hap protein contains a 110 kda internal passenger domain called “haps” and a 45 kda c-termi...

Journal: :Emerging infectious diseases 2015
Jeroen D Langereis Marien I de Jonge

such as sepsis and meningitis, has declined substantially since the introduction of the H. influenzae serotype b vaccine. However, the H. influenzae type b vaccine fails to protect against nontypeable H. influenzae strains, which have become increasingly frequent causes of invasive disease, especially among children and the elderly. We summarize recent literature supporting the emergence of inv...

Journal: :iranian journal of allergy, asthma and immunology 0
farhad esmaily farhad vaezzadeh mohammad kazem sharifi-yazdi

three strains of nontypeable haemophilus influenzae namely nthi-i , nthi-ii and nthi-iii were isolated from the sputum of patients with bronchitis and identified by biochemical, serological and electron microscopy. the polypeptide patterns of isolates were compared and found to have similar sodium dodecyl sulphate-polyacrylamide gel electrophoresis (sds-page) polypeptide patterns, although some...

Journal: :Infection and immunity 1992
J R Gilsdorf H Y Chang K W McCrea L O Bakaletz

Thirty-eight clinical isolates of nontypeable Haemophilus influenzae were tested for the presence of hemagglutinating pili similar to those of H. influenzae type b (Hib) that mediate buccal epithelial cell adherence. Four endogenously hemagglutinating (HA+) strains were identified, and eight additional HA+ variants were obtained from HA- strains by erythrocyte enrichment. All 12 HA+ nontypeable...

2015
Timothy M. VanWagoner Daniel J. Morton Thomas W. Seale Huda J. Mussa Brett K. Cole Paul W. Whitby Terrence L. Stull

Haemophilus influenzae is an important cause of invasive disease. The infant rat is the accepted model of invasive H. influenzae disease. Here, we report the genome sequences of six nontypeable H. influenzae strains that establish bacteremia in the infant rat.

2015
Huda J. Mussa Timothy M. VanWagoner Daniel J. Morton Thomas W. Seale Paul W. Whitby Terrence L. Stull

Nontypeable Haemophilus influenzae is an important cause of human disease. Strains were selected for genome sequencing to represent the breadth of nontypeable strains within the species, as previously defined by the electrophoretic mobility of 16 metabolic enzymes.

Journal: :jundishapur journal of microbiology 0
minoo tavakoli fars science and research branch, islamic azad university, marvdasht, ir iran; fars science and research branch, islamic azad university, marvdasht, ir iran. tel: +98-9126784784 saeed bouzari department of molecular biology, pasteur institute of iran, tehran, ir iran seyed davar siadat department of lung diseases, pasteur institute of iran, tehran, ir iran shahin najar peerayeh department of bacteriology, faculty of medical sciences, tarbiat modares university, tehran, ir iran anis jafari department of molecular biology, pasteur institute of iran, tehran, ir iran

conclusions the pe gene was successfully cloned and confirmed by sequencing. finally, pe was obtained with high concentration. due to high homology and similarity among the pe gene from nthi atcc 49766 and other nthi strains in genbank, we believe that the protein is a universal antigen to be used as a vaccine design candidate and further studies to evaluate its immunogenicity is underway. mate...

Journal: :avicenna journal of medical biotechnology 0

background: the pathogenesis of nontypeable haemophilus influenzae (nthi) begins with adhesion to the rhinopharyngeal mucosa. almost 38-80% of nthi clinical isolates produce proteins that belong to the high molecular weight (hmw) family of adhesins, which are believed to facilitate colonization. methods: in the present study, the prevalence of hmwa, which encodes the hmw adhesin, was determined...

Journal: :Journal of clinical microbiology 2012
K M Hare M J Binks K Grimwood A B Chang A J Leach H Smith-Vaughan

A PCR for protein D (hpd#3) was used to differentiate nontypeable Haemophilus influenzae (NTHI) from Haemophilus haemolyticus. While 90% of nasopharyngeal specimens and 100% of lower-airway specimens from 84 Indigenous Australian children with bronchiectasis had phenotypic NTHI isolates confirmed as H. influenzae, only 39% of oropharyngeal specimens with phenotypic NTHI had H. influenzae. The n...

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