this work is conducted to obtain mechanical properties of microtubule. for this aim, interaction energy in alpha-beta, beta-alpha, alpha-alpha, and beta-beta dimers was calculated using the molecular dynamic simulation. force-distance diagrams for these dimers were obtained using the relation between potential energy and force. afterwards, instead of each tubulin, one sphere with 55 kda weight ...

for the nonlinear analysis of structures using the well known newton-raphson method, the tangent stiffness matrices of the elements must be constructed in each iteration. due to the high expense required to find the exact tangent stiffness matrices, researchers have developed novel innovations into the newton-raphson method to reduce the cost and time required by the analysis. in this paper, a ...

the present study is concerned with optimal shape determination of inhomogeneous and temperature dependent domains under steady state heat conduction. such situations are important in many thermal design problems, especially in shape design of electronic components and chips. in the present paper, we formulate the shape optimization problem based on volume minimization of heat conductive materi...

the concepts of structural optimization was introduced about sixty years ago. smiths from the university of los angeles (california) for the first time has offered the combination of finite element method and optimization techniques to design optimum structures (1960). at present time, this techniques are generally understood and many softwares for this perpose have been developed. in this pape...

saccharomyces cerevisiae (baker’s yeast) can exhibit sustained oscillations during the operation in a continuous bioreactor that adversely affects its stability and productivity. because of heterogeneous nature of cell populations, the cell population balance equation (pbe) can be used to capture the dynamic behavior of such cultures. in this work, an unstructured-segregated model is used for d...

This work is conducted to obtain mechanical properties of microtubule. For this aim, interaction energy in alpha-beta, beta-alpha, alpha-alpha, and beta-beta dimers was calculated using the molecular dynamic simulation. Force-distance diagrams for these dimers were obtained using the relation between potential energy and force. Afterwards, instead of each tubulin, one sphere with 55 KDa weight ...

The aim of this paper is to investigate geometrically nonlinear static analysis of axially functionally graded cantilever beam subjected to transversal non follower load. The considered problem is solved by finite element method with total Lagrangian kinematic approach. The material properties of the beam vary along the longitudinal direction according to the power law function. The finite elem...