biomolecular behavior of tumor cells has become attractive to investigators. p53 as an oncosuppresor gene has been core of various studies and ki67 is a nuclear protein involved in proliferation process. stopping of onco-suppressor function theoretically allows proliferative system to get out of any control. in this case-control study we evaluated 50 patients with non small cell lung cancer, co...

conclusion the technical performance of pet scan is significantly higher than similar technologies for staging and treatment of nsclc. in addition, it might slightly improve the treatment process and lead to a small level of increase in the quality adjusted life year (qaly) gained by these patients making it cost-effective for the treatment of nsclc. results the total annual running cost of a p...

Miliary mottling on chest radiography is seen in miliary tuberculosis, certain fungal infections, sarcoidosis, coal miner’s pneumoconiosis, silicosis, hemosiderosis, fibrosing alveolitis, acute extrinsic allergic alveolitis, pulmonary eosinophilic syndrome, pulmonary alveolar proteinosis, and rarely in hematogenous metastases from the primary cancers of the thyroid, kidney, trophoblasts, and so...

miliary mottling on chest radiography is seen in miliary tuberculosis, certain fungal infections, sarcoidosis, coal miner’s pneumoconiosis, silicosis, hemosiderosis, fibrosing alveolitis, acute extrinsic allergic alveolitis, pulmonary eosinophilic syndrome, pulmonary alveolar proteinosis, and rarely in hematogenous metastases from the primary cancers of the thyroid, kidney, trophoblasts, and so...

aims: the backbone of treatment in advanced non-small cell lung cancer is platinum-based doublet chemotherapy. we intended to compare the effectiveness of two commonly used regimens in real world practice. methods: this single institute, parallel comparative post marketing study included 100 patients with chemo-naïve advanced (stage iiib, iv) non-small cell lung cancer and eastern cooperative o...

cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the efficacy and safety of gemcitabine and cisplatin combination. twentythree pati...

background: cisplatin-based chemotherapy is the standard treatment for advanced non-small cell lung cancer (nsclc). many novel drugs, including gemcitabine, vinorelbine, paclitaxel and docetaxel have been used in combination with cisplatin in this setting. of these drugs, gemcitabine is reported to have a high response rate and acceptable toxicity. the aim of this study was to evaluate the effi...

Background & objective: The histologic distinction of small cell from non-small cell lung carcinoma and correct identification of all subtypes of lung carcinoma are very important in treatment management. The main method for histologic classification of lung tumors is based on morphology. However, in small bronchoscopic biopsies in par...