background the surgical informed consent (sic) is a comprehensive process that establishes an informationbased agreement between the patient and his doctor to undertake a clearly outlined medical or surgical intervention. it is neither a casual formality nor a casually signed piece of paper. the present study was designed to audit the current knowledge and attitudes of doctors towards sic at a ...

While the placebo effect has been studied for a long time, much less is known about its negative counterpart, named the nocebo effect. However, it may be of particular importance because of its impact on the treatment outcomes and public health. We conducted a review on the nocebo effect using PubMed and other databases up to July 2014. The nocebo effect refers by definition to the induction or...

Negative expectations deriving from the clinical encounter can produce negative outcomes, known as nocebo effects. Specifically, research on the nocebo effect indicates that information disclosure about potential side effects can itself contribute to producing adverse effects. Neurobiological processes play a role in the nocebo effect, and this article provides a selective review of mechanistic...

Background The Surgical Informed Consent (SIC) is a comprehensive process that establishes an informationbased agreement between the patient and his doctor to undertake a clearly outlined medical or surgical intervention. It is neither a casual formality nor a casually signed piece of paper. The present study was designed to audit the current knowledge and attitudes of doctors towards SIC at a ...

INTRODUCTION Patients require an accurate knowledge about placebos and their possible effects to ensure consent for placebo-controlled clinical trials is adequately informed. However, few previous studies have explored patients' baseline (ie, pretrial recruitment) levels of understanding and knowledge about placebos. The present online survey aimed to assess knowledge about placebos among patie...

background: pre-operative informed consent is an important aspect of surgery, yet there has been no formal training regarding it in pakistan. this study was done to assess the preoperative informed consent practice. methods: after taking informed permission, a questionnaire was filled in during an interview with 350 patients, who have undergone elective surgical procedures under routine practic...

in recent years, notable measures have been taken to protect the rights of participants in biomedical research in iran. the present study examines possible trends in adherence to ethical codes regarding informed consent after the development of the national code of ethics in biomedical research (ncebr) and establishment of research ethics committees. in this retrospective study, 126 dissertatio...

background: clinical trial is the standard method to assess efficacy of a medical intervention. because of its experimental nature, meaning that subjects are exposed to an intervention with uncertain outcome and according to historical evidences of criminal researches, clinical trial is of something of a lightning rod for ethical concerns. ethical issues surrounding clinical trials are very per...