statement of problem: papillon lefevre syndrome (pls) is a rate autosomal recessive disorder, which is characterized by palmar- plantar hyperkeratosis and rapid periodontal destruction of primary and permanent dentitions. purpose: the aim of the present study was to evaluate the peripheral blood neutrophil function including random locomotion, chemotaxis and oxidative mechanism of killing in a ...

background: leishmaniasis is a worldwide disease prevalent in tropical and sub- tropical countries in the world. characterization of inflammatory responses produced in cutaneous leishmaniasis has not yet been completed. methods: the specific primers were designed for ten pro-inflammatory genes including ccl4, ccl3, tnf-α, il-1α, il-12p35, il-12p40, ccl5, ccr5, il-1β and ifn- γ and their express...

The quantitative changes of the high mobility group (HMG) nonhistone chromosomal proteins in nondividing, differentiated peritoneal exudate neutrophils were identified by their solubility, electrophoretic mobility on both SDS and acetic acid gels, densitometric traces and elution profile on CM-sephadex. The results indicated that in neutrophils, HMGl undergoes a considerable reduction (80%...

background: during the initial phase of an infection, there is an upregulation of inducible nitric oxide synthase in the macrophages for the production of nitric oxide. this is followed by the recruitment of polymorphonuclear leukocytes (neutrophils) which release arginase. arginase competes with inducible nitric oxide synthase for a common substrate l-arginine. objective: to investigate whethe...

protection of the mammary gland against mastitis-causing pathogens is mediated by many factors in thegland and blood circulation. the professional phagocytic cells of bovine udder, polymorphonuclearneutrophils (pmn) and macrophages, comprise the first line of defense against invading mastitis pathogens.most researchers now accept that the pmn is a key factor in the cows’ defense against intrama...

to evaluate the effect of intrauterine cephapirin on treatment of endometritis 39 holstein dairy cows that affected with postpartum endometritis were selected and randomly assigned to two experimental designs. in experiment 1, 6 out of 14 cows were 25 to 30 days after parturition were treated by intrauterine oxytetracycline. another 8 cows were treated by intrauterine cephapirin (metri-care). i...

background & objectives: neutrophils are the most important member of granulocytes & the first line of host defence against micro-organisms. they kill micro-organisms entering the body by phagocytic activity. one of the important phases of phagocytic activity is respiratory burst which can be effected by different drugs such as cimetidine. in this study the effects of cimetidine on respiratory ...

BackgroundAppendicitis is the most common indication for an emergency operation in children's age. Although none of the laboratory values has not high sensitivity and specificity for the diagnosis of appendicitis, leukocyte count and the percentage of segmented neutrophils are most commonly used. The aim of this study was to determine whether there is a statistically significant correlation bet...

Background: During the initial phase of an infection, there is an upregulation of inducible nitric oxide synthase in the macrophages for the production of nitric oxide. This is followed by the recruitment of polymorphonuclear leukocytes (neutrophils) which release arginase. Arginase competes with inducible nitric oxide synthase for a common substrate L-arginine. Objective: To investigate whethe...