iontophoresis of epinephrine for assessment of neuromuscular junction response is a new technique that can improve diagnose of neuromuscular dysfunction. the purpose of this study was to investigate the effects of iontophoresis of epinephrine on neuromuscular junction response. iontophoresis of epinephrine solution (1mg/ml), sodium chloride, calcium gluconate, epinephrine with sodium chloride a...

effects of venom from black scorpion androctonus crasicuda (ac) were determined on isolated chick biventer cervices nerve-muscle and mouse hemidiaphragm preparations using twitch tension method. the isolated nerves were stimulated by electrical stimulator and response to each stimulus was recorded. the venom mainly acted prejunctionally to facilitate neuromuscular activity due to an increase in...

background & aim: to reported a case of ovarian dermoid cyst with abnormal clinical manifestation. case report: we present a 53-year-old woman with loss of muscle strength in lower extremities (in both legs) and gait abnormalities due to ovarian dermoid cyst. the following severe disability and dependence on wheelchair, the patient attended hospital in march 2015 and underwent surgery. currentl...

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neuromuscular diseases are abnormal processes involving cns (central nervous system), pns (peripheral nervous system), nmj (neuromuscular junction), muscle or any combination of these. our goals in neuromuscular disease are maintenance of function, quality of life, educate patient and family, anticipate needs, expect change and prevent or delay complications. limb contractures and scoliosis, we...

a blocker of postsynaptic acetylcholine receptors was isolated from venom of the eastern green mamba dendroaspis angusticeps, by gel filtration, ion-exchange and reverse phase high performance liquid chromatography. the isolated component blocks neuromuscular transmission and responses to exogenously applied acetylcholine in isolated chick biventer cervices preparations. these results suggest t...

hereditary inclusion body myopathy (hibm) is an adult-onset hereditary myopathy, usually with distal onset and quadriceps sparing. this myopathy is autosomal recessive and associated to upd-n-acetylglucosamine-2-epimerase/n-acetylmannosamine kinase (gne) gene mutations. in this study, we report a novel gne homozygous point mutation c.1834t>g that results in amino acid substitution of cysteine 6...

objective neuromuscular disorders (diseases of the motor unit), can cause respiratory problems such as impaired cough reflex, chest deformity, recurrent pneumonia and acute respiratory failure; these are the worst most common complications of these diseases and the leading cause of death in such patients (1, 2). their management hence, very often, entails admission to the pediatric intensive ca...

background postoperative residual blockade, longer duration of action for neuromuscular blockade, and slower recovery were relatively common in elderly patients. objectives we aimed to investigate the safety of train-of-four ratio and clinical tests in the assessment of patient recovery, and to determine the effects of the rocuronium, vecuronium, and cisatracurium on intubation, extubation and ...

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