TO THE EDITOR—We read the letter of Kesav et al [1] with great interest, and we are pleased to see the reflections from our report on neurobrucellosis [2]. We would like to emphasize some important points regarding the diagnosis and treatment of neurobrucellosis. Cerebrospinal fluid (CSF) findings (abnormal tube agglutination of isolation of bacteria) are still one of the most important support...

BACKGROUND Central nervous system involvement is a serious complication of brucellosis with various incidence and various clinical presentations. PATIENTS AND METHODS Hospitalized patients in University Clinical Centre, Clinic for Infectious diseases in Prishtina, with laboratory-confirmed brucellosis, were analyzed, a brucellosis-endemic region. Among the 648 confirmed cases with brucellosis...

OBJECTIVE To investigate whether visual evoked potentials (VEPs) are valuable for distinguishing between brucellosis with or without neurological involvement. METHODS A total of 23 patients who were admitted to the Department of Infectious Diseases and Microbiology, and Neurology, Ministry of Health Ankara Education and Research Hospital, Ankara, Turkey between December 2004 and August 2005 w...

Neurobrucellosis is a rare complication of brucellosis, a common zoonosis with multisystem involvement. Its clinical presentation is quite heterogeneous and diagnosis requires a high index of suspicion in patients from endemic areas. We present two cases of neurobrucellosis with widely varying clinical involvement from a tertiary center in Pakistan. Our case report emphasizes that neurobrucello...

Brucellosis is an endemic zoonotic disease in which neurobrucellosis occurs in 5-10% of cases. Variable clinical and radiological manifestations of neurobrucellosis can mimic those of other diseases. In this report, we present unusual clinical and magnetic resonance imaging (MRI) findings in a patient with neurobrucellosis and unilateral abducens nerve palsy. Her MRI showed punctate leptomening...

Brucellosis is an endemic disease in our country. Neurobrucellosis occurs in 5 to 10% of cases, and can present at any stage of of the disease. This study was undertaken to evaluate clinical, epidemiological and paraclinical aspects of brucellosis with and without neurological manifestations. Data of 30 patients, 15 cases with nervous system involvement (neurobrucellosis) and 15 cases without n...

BACKGROUND Neurobrucellosis is an uncommon complication of brucellosis. The clinical features of neurobrucellosis vary greatly and, in general, tend to be chronic. Many of the laboratory procedures usually employed in the diagnosis of brucellosis frequently give negative results. For these reasons, and because brucellosis is a disease, which is both treatable and curable, the degree of suspicio...

TO THE EDITOR—The recent article by Guven et al [1], titled “Neurobrucellosis: Clinical and Diagnostic Features,” sheds light on many important yet vexing issues in the clinical presentation, diagnosis, andmanagementofarelativelycommon zoonotic infection. The relevance of discussing this issue is understated by the lack of consensus in the diagnosis and management of neurobrucellosis, in combin...

OBJECTIVES To assess the clinical categories, laboratory, radiological findings, and treatment outcomes of patients with neurobrucellosis. METHODS This retrospective study was designed at the Infectious Diseases and Clinical Microbiology Department, Faculty of Medicine of Gaziantep University, Gaziantep, Turkey between 2003 and 2006. In this period, 300 patients with brucellosis were diagnose...