Leprosy is a chronic infectious disease endemic in Iran that mainly involves skin and peripheral nerves. Leprosy has several clinical forms. One of them is “Pure neural leprosy”. The diagnosis of this form is delayed due to lack of clinical signs in other tissues and can lead to permanent deformity. I will discuss my experience for 20 years in the diagnosis and treatment of this form of leprosy...

background the aim of the present study was to compare two analgesic techniques for transrectal ultrasound (trus)-guided biopsy: diclofenac patch versus periprostatic nerve block with 1% lidocaine. objectives to study the efficacy of and compare diclofenac patch and periprostatic nerve block as analgesia in trus-guided prostate needle biopsy. patients and methods in total, 60 patients were pros...

INTRODUCTION Peripheral nerve vasculitis is an important condition which can be diagnostically challenging and is one of the principal current indications for nerve and muscle biopsy. Previous studies have suggested that combined nerve and muscle biopsy (usually of the superficial peroneal nerve and peroneus brevis muscle) produces a higher diagnostic yield than nerve biopsy alone in the invest...

A 14-year-old who had 7episodes of relapsing unita­leral paralysis of facial nerve during 7 year-;. was admit­ted to the hospital. The X-Ray revealed Osteopetrosis, and the bone biopsy was proved this diagnosis. But there was not any bone fracture, or anemia. Pressure over fa­cial nerve caused by condensation of entire facial nerve canal. was detected by tomographia. Probablv intermitant facial...

Sural nerve regeneration and sensation were evaluated in 16 subjects five or more years after fascicular or whole nerve biopsy. Conduction studies demonstrated successful nerve regeneration in all subjects who had whole nerve biopsy. Postbiopsy interrogation revealed no long-term pain or paresthesias but a high incidence of tactile-induced dysesthesias. No significant difference was seen when a...

OBJECTIVE To investigate the additional diagnostic value of sural nerve biopsy of 64 patients in whom chronic inflammatory demyelinating polyneuropathy (CIDP) was considered, as sural nerve biopsy is recommended in the research criteria of an ad hoc subcommittee to diagnose CIDP. METHODS Firstly, the additional diagnostic value of sural nerve biopsy was analysed with multivariate logistic reg...

Muscle and nerve biopsy may be vital diagnostic tools in various neuromuscular disorders. Since these procedures are invasive, it matters to decide when perform a biopsy, which muscle or selected, how interpret the pathologies. This review addresses indications, methods of biopsies, also significant pathological findings frequently encountered pathology.

One hundred seven patients were retrospectively studied from 1992 to 2002 with diabetic neuropathy that underwent peripheral nerve biopsy. Nerve biopsy revealed the underlying histopathology, including cell and humoral-mediated immunological lesions in the majority of patients. When combined with clinical and laboratory studies, nerve biopsy has the potential to assist in the selection of patie...