background: neonatal deaths mostly occur within the first one week and first 24 hours of life from a variety of conditions. objective: to examine the role of significant hypothermia and hypoglycaemia, in addition to some other factors, in neonatal mortality occurring within the first 24 hours of admission.methods: a prospective study of newborn infants hospitalized within the first 24 hours of ...

Background: Neonatal deaths mostly occur within the first one week and first 24 hours of life from a variety of conditions. Objective: To examine the role of significant hypothermia and hypoglycaemia, in addition to some other factors, in neonatal mortality occurring within the first 24 hours of admission.Methods: A prospective study of newborn infants hospitalized within the first 24 hours of ...

The incidence of hypoglycaemia is greatest in the neonatal period, and the condition is usually associated with "small for dates" infants, although rare causes have been described.' Persistent neonatal hypoglycaemia, however, is usually caused by endocrinopathies or disorders of hepatic metabolism.2 We present some ofour experience of endocrine disease presenting as neonatal hypoglycaemia as th...

INTRODUCTION Neonatal hypoglycaemia is a common condition that can cause developmental delay. Treatment of neonatal hypoglycaemia with oral dextrose gel has been shown to reverse hypoglycaemia and reduce admissions to neonatal intensive care for hypoglycaemia. An evidence-based clinical practice guideline was written to guide the use of dextrose gel to treat neonatal hypoglycaemia in New Zealan...

Martin, F. I. R., Dahlenburg, G. W., Russell, J., and Jeffery, P. (1975). Archives of Disease in Childhood, 50, 472. Neonatal hypoglycaemia in infants of insulin-dependent diabetic mothers. Neonatal hypoglycaemia (blood glucose <20 mg/100 ml) occurred in the first 6 hours of life in 25 of 34 infants born to diabetic mothers receiving insulin. Despite severe hypoglycaemia (blood glucose <10 mg/1...

AIM To determine if children born to mothers with diabetes mellitus during pregnancy, who subsequently developed neonatal hypoglycaemia, experienced long-term neurological dysfunction. METHODS Thirteen children with, and 15 without, neonatal hypoglycaemia (blood glucose < 1.5 mmol/l) were randomly selected from a larger cohort and investigated at the age of 8 years. They were also compared wi...

BACKGROUND Neonatal hypoglycaemia is common, affecting up to 15% of newborn babies and 50% of those with risk factors (preterm, infant of a diabetic, high or low birthweight). Hypoglycaemia can cause brain damage and death, and babies born at risk have an increased risk of developmental delay in later life. Treatment of hypoglycaemia usually involves additional feeding, often with infant formul...

BACKGROUND Macrosomia is associated with considerable neonatal and maternal morbidity. Factors that predict macrosomia are poorly understood. The increased rate of macrosomia in the offspring of pregnant women with diabetes and in congenital hyperinsulinaemia is mediated by increased foetal insulin secretion. We assessed the in utero and neonatal role of two key regulators of pancreatic insulin...