introduction: there is no single test as a gold standard for the diagnosis of allergic rhinitis (ar). the aim of this study was to assess the usefulness and validity of nasal smear as a quick, easy and inexpensive diagnostic method for diagnosis of allergic rhinitis. materials and methods: this study was conducted in a university hospital setting. nasal smears were taken from 39 patients with a...

nasal mucosa has an extraordinary nerve supply with unique geometry that encompasses complex physiology. among these, side-specific predilections to the respiratory and autonomic centers are the interesting issues that have been raised about the consequences of the nasal irritations. the aim of the study was an evaluation of how intranasal stimulation influences lung mechanics and determines wh...

Numerous peripheral tissues possess self-sustaining daily biologic rhythms that are regulated at the molecular level by clock genes such as PER1, PER2, CLOCK, and BMAL1. Physiological function of nasal mucosa exhibits rhythmic variability to a day-night environmental cycle. Nevertheless, little is known of the expression and distribution pattern of clock genes in nasal mucosa. The present study...

Background and Objective: Nasal polyp is the most common benign mass of the nasal cavity and it is originated from nasal cavity or sinuses. Cytokeratins (CK) are intermediate filament proteins that provide mechanical support in epithelial cells. The purpose of this study was to compare the expression of cytokeratin 7 in epithelium of nasal polyps and nasal mucosa in chronic rhinosinusitis. Mate...

OBJECTIVES To investigate the expression and distributional patterns of the inhibitor of apoptosis protein (IAP) family and caspase 3 in nasal polyps and normal nasal mucosa and to evaluate the possible effects of the IAP family and caspase 3 on the development of nasal polyps. DESIGN Prospective study. SETTING Tertiary academic institution. PATIENTS Normal inferior turbinate mucosa was o...

Nasal hyperreactivity in nasal allergy conditions is closely related to allergic inflammation, particularly to infiltration by activated eosinophils in the nasal mucosa, observed 4 to 10 hours after a single antigenic challenge. Repeated antigenic challenge in subjects with nasal allergy enhanced nasal hyperreactivity. On the other hand, various therapies including topical steroids, immunothera...

Introduction: There is no single test as a gold standard for the diagnosis of allergic rhinitis (AR). The aim of this study was to assess the usefulness and validity of nasal smear as a quick, easy and inexpensive diagnostic method for diagnosis of allergic rhinitis. Materials and Methods: This study was conducted in a university hospital setting. Nasal smears were taken from 39 patients wit...

BACKGROUND Severe asthmatics are thought to have severer rhinitis than mild asthmatics. A pale nasal mucosa is a typical clinical finding in subjects with severe allergic rhinitis. OBJECTIVE The aim of this study was to investigate whether a pale nasal mucosa affects airflow limitations in the upper and lower airways in asthmatic children. METHODS Rhinomanometry, nasal scraping, and spirome...